FOXQ1

FOXQ1
Identifiers
Aliases	FOXQ1, HFH1, forkhead box Q1
External IDs	OMIM: 612788; MGI: 1298228; HomoloGene: 7359; GeneCards: FOXQ1; OMA:FOXQ1 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	1,314,758 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	31,744,959 bp
RNA expression pattern
	Top expressed in
	parotid gland; ; pylorus; ; pancreatic epithelial cell; ; pancreatic ductal cell; ; endothelial cell; ; skin of arm; ; palpebral conjunctiva; ; skin of hip; ; secondary oocyte; ; skin of thigh;
	Top expressed in
	transitional epithelium of urinary bladder; ; conjunctival fornix; ; pyloric antrum; ; epithelium of stomach; ; hair follicle; ; mucous cell of stomach; ; medullary collecting duct; ; submandibular gland; ; cornea; ; duodenum;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA-binding transcription factor activity; sequence-specific DNA binding; DNA binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus;
Biological process	hair follicle morphogenesis; regulation of transcription, DNA-templated; transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; anatomical structure morphogenesis; cell differentiation; regulation of transcription by RNA polymerase II; negative regulation of neuron apoptotic process;
	Sources:Amigo / QuickGO
Orthologs
	94234
	15220
	ENSG00000164379
	ENSMUSG00000038415
	Q9C009
	O70220
	NM_033260
	NM_008239
	NP_150285
	NP_032265
	Wikidata
View/Edit Human	View/Edit Mouse

Forkhead box Q1 is a protein that in humans is encoded by the FOXQ1 gene. ^[5]

Function

FOXQ1 is a member of the FOX gene family, which is characterized by a conserved 110-amino acid DNA-binding motif called the forkhead or winged helix domain. FOX genes are involved in embryonic development, cell cycle regulation, tissue-specific gene expression, cell signaling, and tumorigenesis (Bieller et al., 2001 [PubMed 11747606]).

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000164379 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000038415 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Forkhead box Q1". Retrieved 2016-03-14.

Function

References

Further reading