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Glutaryl-CoA dehydrogenase (non-decarboxylating)

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Glutaryl-CoA dehydrogenase (non-decarboxylating)
Identifiers
EC no.1.3.99.32
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
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Glutaryl-CoA dehydrogenase (non-decarboxylating) (EC 1.3.99.32, GDHDes, nondecarboxylating glutaryl-coenzyme A dehydrogenase, nondecarboxylating glutaconyl-coenzyme A-forming GDH) is an enzyme with system name glutaryl-CoA:acceptor 2,3-oxidoreductase (non-decarboxylating).[1][2] This enzyme catalyses the following chemical reaction

glutaryl-CoA + acceptor (E)-glutaconyl-CoA + reduced acceptor

The enzyme contains FAD.

References

  1. ^ Wischgoll, S., Taubert, M., Peters, F., Jehmlich, N., von Bergen, M. and Boll, M. (2009). "Decarboxylating and nondecarboxylating glutaryl-coenzyme A dehydrogenases in the aromatic metabolism of obligately anaerobic bacteria". J. Bacteriol. 191 (13): 4401–4409. doi:10.1128/JB.00205-09. PMC 2698508. PMID 19395484.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  2. ^ Wischgoll, S., Demmer, U., Warkentin, E., Gunther, R., Boll, M. and Ermler, U. (2010). "Structural basis for promoting and preventing decarboxylation in glutaryl-coenzyme a dehydrogenases". Biochemistry. 49 (25): 5350–5357. doi:10.1021/bi100317m. PMID 20486657.{{cite journal}}: CS1 maint: multiple names: authors list (link)