Talk:Escherichia virus T4

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This article was the subject of a Wiki Education Foundation-supported course assignment, between 18 August 2020 and 4 December 2020. Further details are available on the course page. Student editor(s): Jnashl24. Peer reviewers: Lilsharplilac, AlveoliRavioli, Bruno021920, EthosNap.

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Wiki Education Foundation-supported course assignment

This article was the subject of a Wiki Education Foundation-supported course assignment, between 2 September 2019 and 20 December 2019. Further details are available on the course page. Student editor(s): Gv2959.

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Request for expansion

Yah! 😝 T4 is an important virus, especially in the field of genetics. Please expand this article if you have any more relevant information. Thanks. Mushin ^talk 17:13, 12 January 2006 (UTC) and has multi spherical sides and shapes to it it also has more strands of dna in it th[reply]

T4 infects O157:H7

I don't think this is true, and it should probably be deleted. See here: J Biomed Sci. 1998 Sep-Oct;5(5):370-82. Characterization of a phage specific to hemorrhagic Escherichia coli O157:H7 and disclosure of variations in host outer membrane protein ompC. Yu et al.

http://content.karger.com/ProdukteDB/produkte.asp?Aktion=ShowAbstract&ArtikelNr=25351&Ausgabe=226128&ProduktNr=224178 —The preceding unsigned comment was added by 207.112.53.107 (talk) 21:14, 17 February 2007 (UTC).[reply]

I think that in its interesting features it should just say "It infects E. coli" with a proper citation until a verifiable source for E.coli O157:H7 can be found. Any objections? Alfonso Muñoz-Pomer Fuentes 06:20, 20 April 2007 (UTC)[reply]

The phage is supposed to inject its DNA into the bacterial cell, according to the information given here. if it needs energy for that, the in must have some source of energy, like, say, ATP. but it does not have any organelles at all! how can it inject the DNA into the host? Please update this. it would be better if this article was expanded.

Thanks. 59.92.153.79 (talk) 02:23, 22 December 2007 (UTC)[reply]

This, indeed, we don't know much about. The phage can use ATP in loading its genome into its capsid, so it may store energy for injection, I don't know. Helpful videos. Also, the phage is never absorbed into the cell, the article doesn't seem conclusive about that. I agree w/Alfonzo, we need a source for the specific strain. peerlessblue (talk) 06:56, 3 February 2009 (UTC)[reply]

Interesting. Clearly there is little ATP in T4/T6, it may or may not contain primitive polymer motor proteins. However, there is a spring or motor that powers the actual injection of its DNA into the host bacterium. This can be seen clearly in the first animation at the Helpful videos link above, animations showing a molecular view. Presumably the spring is compressed by ATP or motor functions associated with organelles in the host bacterium when it creates the viruses. Or else it is a primitive but effective motor to drive the insertion of the needle into the outer bacterium membrane. Unfortunately, the article fails to show the spring clearly and fails to describe the injection process. Next to the co-option of the bacterial contents, and its self-assembly through stereospecific autocatalysis^[1], possibly aided by motor microtubules, I think injection^[2]^[3] is the most interesting feature. I agree that the article should describe this in more detail. I wish I had the requisite knowledge. Most of us editors are not specialists.

Notes

^ Enantioselective autocatalysis. Spontaneous resolution and the prebiotic generation of chirality, in Origins of Life.
^ The bacteriophage T4 DNA injection machine, in Current Opinion in Structural Biology.
^ Crystallographic insights into the autocatalytic assembly mechanism of a bacteriophage tail spike, Purdue University.

David Spector 00:39, 23 March 2010 (UTC)[reply]

purpose and origin data please

there is nothing here on what it does in a given body and where it comes from, someone please supply this page with more data relevant to this please. —Preceding unsigned comment added by Murakumo-Elite (talk • contribs) 06:06, 3 April 2008 (UTC)[reply]

The T-Evens bacteriophages T2, T4, T6

T2, T4, and T6 bacteriophages are all morphologically complex viruses infecting e. coli. They all look the same and are apparently constructed identically. It would be nice to know how they differ (if they were actually the same, presumably they would not have these different names). David spector (talk) 23:28, 9 December 2009 (UTC)[reply]

Even over a year later, it would still be interesting. David Spector 00:41, 23 March 2010 (UTC)[reply]

Even after almost 10 years, the articles should say something about this. There are no experts around? Also, the section "Infection process" should include the word "injection", since that is exactly what the tevens do. It is an amazing mechanism, which can be used to administer medication and help build nanomechanisms. David Spector (talk) 16:29, 12 March 2019 (UTC)[reply]

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History of imaging?

This virus is one of the most iconic images of imaging microscopy. What's the history to it? When did we first see recognisable images giving this shape and structure? Andy Dingley (talk) 09:47, 30 May 2018 (UTC)[reply]

Changed Page Title to Escherichia virus T4

The International Committee on Taxonomy of Viruses changed the taxonomy of this species to Escherichia virus T4 in 2015. I have edited the page and page title to reflect this. The page should reflect current taxonomic definition. AsimovtheCat (talk) 18:25, 13 December 2018 (UTC)[reply]

Proposing merge from T-even bacteriophages to Escherichia virus T4

Merge - T-even bacteriophages is about three of the strains/member viruses/isolates of the species Escherichia virus T4. See discussion also at Talk:Tevenvirinae#Duplicate Article --Nessie (talk) 19:01, 26 December 2018 (UTC)[reply]

This article needs attention

This article needs serious attention. Many sentences read strange, some are almost unintelligble. In the first paragraph we learn that T4 contains around 160 genes, later that it encodes 289 proteins. Could someone who knows T4 and is proficient in English please take this on? MagnusPalmblad (talk) 12:19, 14 August 2020 (UTC)[reply]

A Commons file used on this page or its Wikidata item has been nominated for deletion

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T4 phage EM.jpg

Participate in the deletion discussion at the nomination page. —Community Tech bot (talk) 19:29, 9 February 2021 (UTC)[reply]

[1] Enantioselective autocatalysis. Spontaneous resolution and the prebiotic generation of chirality, in Origins of Life.

[2] The bacteriophage T4 DNA injection machine, in Current Opinion in Structural Biology.

[3] Crystallographic insights into the autocatalytic assembly mechanism of a bacteriophage tail spike, Purdue University.

[1]

[2]

[3]