Saw him backstage in 1993 with his guitar tech and i looked at his collection of Jackson guitars that he used during the gig and i asked him which is your favorite one he said "probably my signature king v with the megadeth sticker on the wing".

Listed on Reverb.com on November 4, 2019. It bears a white tape label reading "G PDL 05" on the footswitch, while the right top corner side has a blue tape label reading "DM 040".

This Boss MT-2 Metal Zone is Owned by Dave Mustaine, frontman for the legendary metal band Megadeth.

[...]

SN: FL61715. MIJ. Markings on the front. Gaff tape on the front.

Dave talks about his love of the Flying V and behind him you can see he's playing through a Marshall JVM Series JVM410H amp head.

Dave Mustaine likely used various Marshall JCM800 2203 amp heads during the recording of Megadeth's first three to four albums. According to GroundGuitar, he paired these amps with DeCuir Cabinets featuring Celestion speakers.

According to Megadeth guitarist Chris Broderick, he and Dave Mustaine have nearly identical live rigs. At (7:51), he says, “Right now, we're running straight into…into Marshall cabinets loaded with the Vintage 30s. It's just your traditional thrash setup. That's what we're out here to do, so we're doing it.”

Rust in Peace is tortex yellow through and through

Mustaine also uses custom Dunlop Tortex .73mm. This can be seen even back in their videos at Rock In Rio 1991 (tons of them on his mic stand)

“I've played Marshall forever,” Megadeth founder Dave Mustaine says at (3:52). “It's just I established the band on Marshall sound.”

At 2:56 in this video is an awesome shot of Dave Mustaine of Megadeth, and Metallica playing his B.C. Rich Bich in the song' Last Rites/Loved to Deth'.

Megadeth uses the Digitech GSP 1101 Multi Effects Processor as a preamp. At (3:29) Megadeth’s guitar player Chris Broderick says, “The pre-amp, I think that's also done just for simplicity and ease, so we can get a diverse set of tones but still keep it simple. We don't need a ton of different amps breaking down night after night.”

In this image, Mustaine can be seen with a Gibson SG in a Cherry finish.

These amps were designed in part with Line 6 and Dave Mustaine. There were digital amps based on a 1967 Marshall Plexi. It has 4 channels; Clean, Signature (based on his own tone), Megadrive, and Plexi. It also comes with built-in effects.

This amp was used on United Abominations, and the following tour, until he switched to Marshall amps.

In the image sourced from Wattpad, Dave Mustaine is seen holding a B.C. Rich Warlock guitar, likely from his endorsement deal with B.C. Rich during the early Megadeth years.

Here is a picture of Mustaine holding an Ibanez Destroyer, during the Metallica days.

Also Mustaine himself has verified on his Twitter that he used a Destroyer.

https://twitter.com/davemustaine/status/718058716537491456?lang=en

In the picture, Dave Mustaine is performing live with the Dean V Dave Mustaine - Angel Of Death.

In the user-uploaded photo, Dave Mustaine is seen with a Gibson Korina Flying V Electric Guitar. This guitar features an Explorer-style headstock, signature Mustaine pickups, a black finish with gold tuners and bridge, and E-335 style inlays.

This video at 0:26 is a great shot of Dave Mustaine of Megadeth playing his Jackson King V Doubleneck guitar for the song 'In My Darkest Hour'.

Dave Mustaine and Kiko Loureiro use this amplifier in jam room of Megadeth shows (Dystopia world tour 2016)

Dave Mustaine has been using the Fractal Axe-Fx II Guitar Effects Processor since 2012, as noted in "Dave Mustaine's Guitars and Gear" on GroundGuitar.

Dave played a 6-string green BC Rich Bich in 1985

So on to Th1rt3en, what did you use amp-wise? ** For the rhythms it was a mix of the Diezel VH4** and the Bogner Uberschall. It was a very good combination. I felt they complimented each other really well. And for the leads it was just the Bogner Uberschall. Those were [producer] Johnny K’s amps and those were amps that he really liked. When we looked at how those amps sounded in the mix, they definitely fit the sound the best out of all the amps we had.

Dave is seen with his signature model ESP DV8.

Dave Mustaine has stated that the Jackson V Number One has been his primary guitar for nearly all recordings since the "Peace Sells... but Who's Buying?" album, as evidenced by a user-uploaded photo on Jacksonguitarpalace.

Throughout this video, Dave Mustaine demonstrates his signature Zoom G2.1DM pedal.

at 0:40, he mentions he has used this amp

The KV1 line was produced from 1996 to 2001, and it was relatively big commercial success. Dave himself still prefered his old Customs over the KV1, but he did use a couple of them nonetheless.

For years Dave Mustaine, the legendary charismatic leader of Megadeth, relied on our passive JB and Jazz humbuckers to record some of the most influential riffs in the history of Metal. But like most extreme players, eventually you just want more.We worked with Dave to voice a set of active humbuckers that deliver the distinct tonal character of the JBJazz combo but with extra ferocity and gain. The Dave Mustaine LiveWire set is perfect for players who want to try active pickups without drastically changing the tone of the passive pickups theyve become accustomed to. The smooth upper midrange crunch of the JB and the articulate warmth and clarity of the Jazz neck remain intact while the custom tuned active preamp delivers the increased output and touch sensitivity only an active pickup can provide. A unique covered passive humbucker look embossed with Daves signature also ensures these will look and sound great in any guitar.We include pots, mounting hardware, capacitors (active pickups require a special cap value), battery clip, stereo output jack, and wire needed for installation.

Dave Mustaine and Marty Friedman used the CAE 3+ SE preamp for the "Countdown To Extinction" and "Youthanasia" studio albums and corresponding tours.

Dave has used this guitar while playing Holy Wars on the metal tour of the year with Lamb Of God, Trivium and In flames.

During the 1980s, Dave Mustaine used various B.C. Rich guitar models, including the Ironbird, which he played in promotional videos for B.C. Rich.

Dave has used a natural explorer during the song Trust on the metal tour of the year.