Strain information  NBRP Rat No: 0116  Strain name: LEXF7C/Stm  Commmon Name: LEXF7C Rat Genome Database Principal Investigator:  Ryoji Hokao  Institute for Animal Reproduction       1103, Fukaya, Kasumigaura,     300-0131 Ibaraki     Japan Tel: 029-897-0631    Fax: 029-897-0633 Email: [email protected] Preservation Status:   Embryo        Sperm       Living Animals Coat Color  black hooded (a,B,C,h,R) Inbred Generations   Usage Restrictions   Genetic Status   Inbred  Segregating   Congenic   Consomic   Recombinant   Coisogenic   Spont. Mutant  Transgene  Ind. Mutant  Category Other  Comercial Availability Research Category   Diabetes Obesity  Neurobiology  Ophthalmology   Dentistry  Cardio Hypertension  Cancer  Metabolism  Otorhinology  Immunology  Infectious  Osteosis   Internal Organ  Dermatology   Reproduction   Development  Behavior  Hematology  Urology   Pharmacology  Research Area Others   Control Strain  Marker Strain Gene Affected Origin The LEXF/FXLE RI strain set has been established by Shisa et al at Saitama Cancer Center Research Institute since 1985. This RI set consists of 34 RI strains derived by reciprocal crossing of LE/Stm and F344/Stm. Strain characteristics The RI strains are useful genetic tool in gene mapping and analysis of complicated trait genetic diseases. Breeding Conditions Good breeding performance. Sib mating. Genotyping References Shisa H, Lu L, Katoh H, Kawarai A, Tanuma J, Matsushima Y, Hiai H. The LEXF: a new set of rat recombinant inbred strains between LE/Stm and F344. Mamm Genome. 1997 May;8(5):324-7. Lu LM, Shisa H, Tanuma J, Hiai H. Propylnitrosourea-induced T-lymphomas in LEXF RI strains of rats: genetic analysis. Br J Cancer. 1999 May;80(5-6):855-61. Voigt B, Kuramoto T, Mashimo T, Tsurumi T, Sasaki Y, Hokao R, Serikawa T. Evaluation of LEXF/FXLE rat recombinant inbred strains for the genetic dissection of complex traits. Physiol Genomics. 2008 Feb 19;32(3):335-42. Additional strain information LEXF RI strains