Osteogenic Differentiation
MSCgo™ Osteogenic XF Differentiation Media and the MSCgo™ Rapid Osteogenic XF Differentiation Media contain all the growth factors and supplements necessary for the directed differentiation of hMSCs. MSCgo™ Osteogenic XF was validated from various tissues including bone marrow (BM-hMSC), adipose tissue (AT-hMSC), and wharton jelly (WJ-hMSC).
Sample Data

Figure 1: Relative expression (RT-PCR) of osteocyte markers after 10 days of osteogenesis of hMSC using MSCgo™ Osteogenic XF. Osteogenic markers were upregulated whereas an undifferentiated hMSC marker (CD-105) was downregulated. BGLAP represents a maturation state of osteogenesis.

Figure 2: Positive Alizarin staining is observed, indicates of mature osteocytes after a 28 day differentiation assay of hMSC-AT using MSCgo™ Osteogenic XF medium

Figure 3: MSCgo™ Osteogenic XF led to highest expression of osteogenic markers and lowest expression of un-differentiated hMSC marker (CD-105) in comparison to commercial media. BGLAP represents a maturation state of osteogenesis.
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MSCgo™ Osteogenic Differentiation Medium
Complete, serum-free, xeno-free, ready-to-use medium
Optimized for directed differentiation of hMSCs to osteoblasts
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MSCgo™ Rapid Osteogenic Differentiation Medium
Complete, serum-free, xeno-free, ready-to-use medium
Optimized for faster directed differentiation of hMSCs to osteoblasts
Learn More