The plot of the episode follows Peter as he goes into the doctor for a flu shot only to stick around for a prostate exam. In true Family Guy fashion Peter believes that his doctor was trying to rape him. Eventually Peter takes his doctor to court, and gets his medical license revoked. By the end Peter does understand that the exam was just that, and that he was in need of the exam all along. The other story told in the episode starts with Stewie having his stuffed animal destroyed by a dog, only to be sewn back together by Lois. The combined action of the restoration of his doll and a nice meal show Stewie that his mother is not his enemy but his best friend. After some nice bonding time, Lois finds that Stewie is just too clingy, leading her to homicidal thoughts. In the end things go back to the way they started as Lois ignores Stewie's cries and he hurts himself.
The Stewie/Lois story was really kind of funny. This bit was a nice window in on parenting. Although parents want to be closer to their children, they can find that it isn't as good of an idea as they initially thought. And after watching four seasons of Stewie venturing to kill his mother, it was just odd and strangely humorous to see him loving her. Plus, this new relationship led to a couple great confrontations between Stewie and Brian. As always Brian is working his best to impress Lois, while Stewie's newfound love for his mother springs jealousy - what follows are a couple hilarious scenes with the two competing for her (one argument ends with Stewie screaming in Spanish which is very funny).
The other storyline is where our big problem is with the episode. We know that the story comes full circle and Peter realizes that he needs the prostate exam, but that does not excuse the rather frank and explicit rape jokes leading to this revelation. One of the scenes in particular - Peter giving his trumped up testimony of being violated in court - went from creepy and awkward to just plain disturbing. A black and white dream depicts Peter's interpretation of the "incident" which is just graphic depictions of him being uncomfortably groped, probed and kissed. I know that a couple of the flashbacks were direct movie parodies, but it was just wrong. Whereas a prostate joke can be offensive and funny, a rape joke can almost never be both. If MacFarlane needed a good idea of a prostate joke, all he had to do was look to castmate Seth Green's show Robot Chicken to see Optimus Prime dying of prostate cancer - playing out like a giant public service announcement (in the episode "Junk in the Trunk").
Here at IGN we are all fans of Family Guy, and we admit that some of the better episodes and jokes are those that are offensive (e.g., the amazing HIV barbershop quartet song or the episode "When You Wish Upon a Weinstein"). But it is tough to tell people to watch a television program that treats these real issues with such nonchalance. We are all hoping that the rest of the season is funnier than this episode - please, MacFarlane, think before you write.