Alpha,gamma-cyclic peptide ensembles with a hydroxylated cavity

Org Biomol Chem. 2009 Nov 7;7(21):4358-61. doi: 10.1039/b911247m. Epub 2009 Aug 26.

Abstract

Here we describe a self-assembling alpha,gamma-cyclic tetrapeptide that contains the 4-amino-3-hydroxytetrahydrofuran-2-carboxylic acid, in which the hydroxy group is pointing towards the inner cavity of the resulting dimers.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acids / chemistry
  • Dimerization
  • Hydroxylation
  • Isomerism
  • Models, Molecular
  • Molecular Conformation
  • Peptides, Cyclic / chemistry*

Substances

  • Amino Acids
  • Peptides, Cyclic