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Role of copper in our body




                   Made by:
                   Magdalena Wnuk
                   Nicolas Węgrzyn
Role of copper in our body
Dietary reference intakes for copper
  Tolerable Upper Intake Levels (UL)**
                Age       Male      Female     Pregnant   Lactating

              1-3 yrs.   1000 µg    1000 µg

                4-8      3000 µg    3000 µg

               9-13      5000 µg    5000 µg

               14-18     8000 µg    8000 µg    8000 µg    8000 µg

               19-50     10000 µg   10000 µg   10000 µg   10000 µg

               51-70     10000 µg   10000 µg

                70+      10000 µg   10000 µg

  **UL = The maximum level of daily nutrient intake that is likely to pose
  no risk of adverse effects. Unless otherwise specified, the UL
  represents total intake from food, water, and supplements.
Top 10 foods highest in copper
1: Liver

2: Oysters

3: Sesame Seeds and Tahini

4: Cocoa Powder and Chocolate

5: Nuts

6: Calamari and Lobster

7: Sunflower Seeds

8: Sun Dried Tomatoes

9: Roasted Pumpkin and Squash Seeds

10: Dried Herb
How much do we really eat everyday?

  Breakfast:                         Lunch:
  • Flakes (52g) – 1,1mg             • Salad (55g) – 0mg
  • Juice (250g) – 0,3mg             • Beef (160g) – 23mg
  • Milk (250g) – no data            • Potatos (180g) – 0mg
  • Yogurt (150g) – 0,1mg            • Dark chocolate (100g) – 1,8mg
                    Dinner:
                    • Veal (100g) – 12mg
                    • Buckwheat (170g) – 1,9mg
                    • Pineapple (240g) – 0,3mg

 Summary – the real daily consumption of copper approximately is – 40,5mg
Clinical Effects of Inadequate Intake
  Frank copper deficiency in humans is rare, but has been found in a
  number of special conditions. It has been observed:
  • premature infants fed milk formulas
  • infants recovering from malnutrition associated with chronic
     diarrhea and fed cow’s milk

  Symptoms accompanying the copper deficiency :
  • normocytic
  • hypochromic anemia
  • leukopenia
  • neutropenia
  • osteoporosis
Factors affecting the copper requirement
                     Zinc
Zinc intakes, well in excess of the amount normally found in the diet,
can decrease copper absorption in adults
Factors affecting the copper requirement
                    Iron
High iron intakes may interfere with copper absorption in infants:
• low concentrations of iron absorbed more copper
• higher iron concentration less absorption
Factors affecting the copper requirement
                 Fructose

Studies in rats demonstrated that diets very high in fructose were
associated with increased severity of copper deficiency in rats, but a
similar effect was not observed in pigs
Osteoporosis
One factor contributing to bone density loss in the elderly may be subclinical
magnesium (Mg), zinc (Zn) and/or copper (Cu) deficiencies due to a reduced
dietary intake and reduced absorption of these micronutrients. Mg, Zn
and Cu are essential cofactors for enzymes involved in thesynthesis of
various bone matrix constituents.



                           Normal       Osteopenia     Osteoporosis

         Copper (mg/l)    1.60 ± 0.08    1.59 ± 0.09    1.54 ± 0.12
Thank You for Your Atention

More Related Content

Role of copper in our body

  • 1. Role of copper in our body Made by: Magdalena Wnuk Nicolas Węgrzyn
  • 3. Dietary reference intakes for copper Tolerable Upper Intake Levels (UL)** Age Male Female Pregnant Lactating 1-3 yrs. 1000 µg 1000 µg 4-8 3000 µg 3000 µg 9-13 5000 µg 5000 µg 14-18 8000 µg 8000 µg 8000 µg 8000 µg 19-50 10000 µg 10000 µg 10000 µg 10000 µg 51-70 10000 µg 10000 µg 70+ 10000 µg 10000 µg **UL = The maximum level of daily nutrient intake that is likely to pose no risk of adverse effects. Unless otherwise specified, the UL represents total intake from food, water, and supplements.
  • 4. Top 10 foods highest in copper 1: Liver 2: Oysters 3: Sesame Seeds and Tahini 4: Cocoa Powder and Chocolate 5: Nuts 6: Calamari and Lobster 7: Sunflower Seeds 8: Sun Dried Tomatoes 9: Roasted Pumpkin and Squash Seeds 10: Dried Herb
  • 5. How much do we really eat everyday? Breakfast: Lunch: • Flakes (52g) – 1,1mg • Salad (55g) – 0mg • Juice (250g) – 0,3mg • Beef (160g) – 23mg • Milk (250g) – no data • Potatos (180g) – 0mg • Yogurt (150g) – 0,1mg • Dark chocolate (100g) – 1,8mg Dinner: • Veal (100g) – 12mg • Buckwheat (170g) – 1,9mg • Pineapple (240g) – 0,3mg Summary – the real daily consumption of copper approximately is – 40,5mg
  • 6. Clinical Effects of Inadequate Intake Frank copper deficiency in humans is rare, but has been found in a number of special conditions. It has been observed: • premature infants fed milk formulas • infants recovering from malnutrition associated with chronic diarrhea and fed cow’s milk Symptoms accompanying the copper deficiency : • normocytic • hypochromic anemia • leukopenia • neutropenia • osteoporosis
  • 7. Factors affecting the copper requirement Zinc Zinc intakes, well in excess of the amount normally found in the diet, can decrease copper absorption in adults
  • 8. Factors affecting the copper requirement Iron High iron intakes may interfere with copper absorption in infants: • low concentrations of iron absorbed more copper • higher iron concentration less absorption
  • 9. Factors affecting the copper requirement Fructose Studies in rats demonstrated that diets very high in fructose were associated with increased severity of copper deficiency in rats, but a similar effect was not observed in pigs
  • 10. Osteoporosis One factor contributing to bone density loss in the elderly may be subclinical magnesium (Mg), zinc (Zn) and/or copper (Cu) deficiencies due to a reduced dietary intake and reduced absorption of these micronutrients. Mg, Zn and Cu are essential cofactors for enzymes involved in thesynthesis of various bone matrix constituents. Normal Osteopenia Osteoporosis Copper (mg/l) 1.60 ± 0.08 1.59 ± 0.09 1.54 ± 0.12
  • 11. Thank You for Your Atention