Syphilis
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Syphilis PPT
Syphilis PPTali7070 Syphilis is a contagious bacterial infection caused by Treponema pallidum that is transmitted through direct contact with a chancre sore, usually during sexual contact. It progresses through primary, secondary, latent, and tertiary stages if left untreated. Symptoms vary by stage but may include sores, rashes, and damage to internal organs over time. Diagnosis involves tests of fluids from sores, blood tests, and spinal taps. Treatment is with antibiotics but damage cannot be reversed. Prevention involves safe sex practices and regular testing to catch the infection early.
Syphilis lecture PP
Syphilis lecture PPAmr Eldakroury This document discusses syphilis, a sexually transmitted disease caused by the spirochete Treponema pallidum. It defines syphilis and describes the causative organism. It discusses the modes of transmission for acquired and congenital syphilis. The clinical stages of syphilis are outlined including primary, secondary, latent, and tertiary syphilis. The diagnosis, treatment, and prognosis of syphilis are summarized. Congenital syphilis is also described. References are provided.
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Syphilis
Syphilisvikramsingh1295 Syphilis is a sexually transmitted infection caused by the bacterium Treponema pallidum. It presents in stages, beginning with a painless sore and progressing to a rash and lesions on mucous membranes if left untreated. Without treatment, it can spread throughout the body and cause damage to internal organs, nerves, and blood vessels. Syphilis is treated with antibiotics, most commonly penicillin, with the treatment depending on which stage the infection is in. Congenital syphilis can occur if an infected mother transmits the bacterium to her fetus during pregnancy.
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Candida
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Syphilis(Treponema pallidum)
Syphilis(Treponema pallidum)heart4kurd Syphilis is a chronic bacterial infection caused by the bacteria Treponema pallidum that is primarily transmitted through sexual contact. It progresses through three stages - primary, secondary, and tertiary - if left untreated. Primary syphilis involves skin sores, secondary syphilis involves rashes and mouth sores, and tertiary syphilis can damage internal organs. Syphilis is diagnosed through tests that detect antibodies produced in response to the infection. While antibiotics can cure it in its early stages, later stages may cause permanent damage without treatment.
Zygomycosis
ZygomycosisMicrobiology Zygomycosis is a fungal infection caused by inhaling spores from mold fungi of the class Zygomycetes, like Mucorales and Entomophthorales. These fungi are found in soil and decaying organic matter. Zygomycosis most commonly affects the sinuses or lungs and can disseminate in immunocompromised individuals like those with diabetes, cancer, or AIDS. Symptoms depend on the infected area but may include cough, fever, sinus pain, and facial swelling. Diagnosis involves examining samples from infected tissues under a microscope and culturing the fungi. Treatment requires antifungal medications like amphotericin B and sometimes surgery to remove infected tissue.
Syphilis 
Syphilis Nibin Murukesh This document summarizes syphilis, caused by the spirochete Treponema pallidum. It is transmitted sexually or vertically. Primary syphilis presents as a chancre, which disseminates and causes secondary syphilis skin lesions. Without treatment, it can progress to latent, tertiary cardiovascular, or neurosyphilis stages involving the brain, heart and blood vessels. Diagnosis involves clinical history, exams, and serological tests detecting nontreponemal and treponemal antibodies. Penicillin is the treatment, while abstinence and safe sex practices prevent transmission.
Dermatophytes
Dermatophytesrubaiya kabir Dermatophytes are fungi that infect keratinized tissues like skin, hair, and nails. There are three genera of dermatophytes: Microsporum, Trichophyton, and Epidermophyton. They produce enzymes that allow them to invade keratinized tissues. Dermatophyte infections can occur on the scalp (tinea capitis), beard (tinea barbae), body (tinea corporis), groin (tinea cruris), hands (tinea manum), and feet/nails (tinea pedis/unguium). Diagnosis involves microscopic examination of skin or nail samples in potassium hydroxide (KOH), culture, and sometimes PCR.
Syphilis
SyphilisNuthan DeSouza Treponema pallidum is a spirochete bacterium that causes syphilis. It is thin and motile, seen under darkfield microscopy. Syphilis is transmitted sexually or from mother to fetus. It has three stages - primary, secondary, and tertiary - with characteristic lesions developing at each stage like chancres. Diagnosis involves serological tests detecting antibodies like VDRL and RPR. Penicillin is the treatment of choice.
Copy of rpr test for syphilis
Copy of rpr test for syphilisandreei The RPR test is a screening test for syphilis that detects nonspecific antilipid antibodies produced in response to infection with Treponema pallidum, the bacterium that causes syphilis. It is a qualitative slide agglutination test where carbon particles coated with lipids are agglutinated by reagin antibodies in the serum sample, making the charcoal clump visibly. A reactive result indicates the presence of reagin and potential syphilis infection, while a non-reactive result means no reagin was detected. Only serum or plasma samples should be used to avoid interference.
Treponema pallidum 
Treponema pallidum RuksanaRukku This document provides information on Treponema pallidum, the spirochete bacterium that causes syphilis. It discusses the morphology, cultivation, antigenic structure, and pathogenesis of T. pallidum. It also describes the stages of syphilis infection including primary, secondary, and tertiary syphilis. The document concludes with an overview of laboratory diagnosis of syphilis including microscopy, staining techniques, and various serological tests.
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Lymphatic filariasispushpamanjari 1. Lymphatic filariasis is caused by parasitic roundworms Wuchereria bancrofti and Brugia malayi, which are transmitted by mosquitoes.
2. India accounts for 38% of the global burden of lymphatic filariasis, with over 473 million people living in endemic areas and 31 million microfilaria carriers.
3. The life cycle of W. bancrofti involves microfilariae infecting humans and being taken up by mosquitoes during blood feeding, where they develop over 10-14 days before infecting another human.
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Syphilis
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SyphilisNuthan DeSouza Treponema pallidum is a spirochete bacterium that causes syphilis. It is thin and motile, seen under darkfield microscopy. Syphilis is transmitted sexually or from mother to fetus. It has three stages - primary, secondary, and tertiary - with characteristic lesions developing at each stage like chancres. Diagnosis involves serological tests detecting antibodies like VDRL and RPR. Penicillin is the treatment of choice.
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Copy of rpr test for syphilisandreei The RPR test is a screening test for syphilis that detects nonspecific antilipid antibodies produced in response to infection with Treponema pallidum, the bacterium that causes syphilis. It is a qualitative slide agglutination test where carbon particles coated with lipids are agglutinated by reagin antibodies in the serum sample, making the charcoal clump visibly. A reactive result indicates the presence of reagin and potential syphilis infection, while a non-reactive result means no reagin was detected. Only serum or plasma samples should be used to avoid interference.
Treponema pallidum
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Rickettsiae
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Lymphatic filariasis
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2. India accounts for 38% of the global burden of lymphatic filariasis, with over 473 million people living in endemic areas and 31 million microfilaria carriers.
3. The life cycle of W. bancrofti involves microfilariae infecting humans and being taken up by mosquitoes during blood feeding, where they develop over 10-14 days before infecting another human.
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Syphilis
- 1. AINA SYAHIRAH BINTI ALI BADERUDIN NURUL SYAKIRA BINTI KAMARUDIN NUR ANIS SYAFIQAH BINTI NORAZLI HANI IZZATI SYAZA BINTI ISMAIL NUR ATIKAH AMIRA BINTI RANI SYPHILIS
- 2. SYPHILIS BACKGROUND Is a sexually transmitted disease (STD) Disease progresses in stages May become chronic without treatment
- 3. ETIOLOGY/ RISK FACTORS Caused by T.pallidum Spirochete bacterium Association with HIV Cannot be viewed by normal light microscopy (Darkfield microscopy) Syphilitic lesions on the genitals enhance HIV transmission Cannot be cultured in vitro Cockscrew-shaped, motile microaerophilic bacterium Spread in utero after 10th week of pregnancy
- 4. PATHOGENESIS Penetration • T.pallidum enters the body via skin and mucous membranes through abrasions during sexual contact • Transmitted transplacentally from mother to fetus during pregnancy Dissemination • Travels via the circulatory system • Invasion of the central nervous system (CNS) can occur during any stage of syphilis. Etiologic agent: Treponema pallidum
- 5. SIGNS/SYMPTOMS 1. Primary Syphilis Lesion/”chancre” What is chancre? -Progresses from macule to papule to ulcer -Painless indurated lesion
- 6. 2. Secondary Syphilis Blood-borne bacteria spread to all major organ systems Flu-like symptoms Mucous patches Bilateral symmetric rashes Condylomata lata (wart-like lesions)
- 7. 3. Latent Syphilis Immune system is surpressing infection Showing no symptoms 4. Tertiary Syphilis Untreated patients are lead to the last stage of syphilis Gummatous lesions Cardiovascular syphilis
- 8. INVESTIGATIONS Clinical history • History of syphilis • Known contact to early case of syphilis Physical Examination • Oral cavity • Palms and soles • Genitalia & perianal area • Neurologic examination Laboratory diagnosis • Identification of T.pallidum in lesion exudates or tissue • Darkfield microscopy • Test to detect T.pallidum
- 9. MANAGEMENT/TREATMENT Penicillin Allergic- other oral antibiotics (Azithromycin) PREVENTIONS o Patient counseling and education o Management of sex partners o Screening recommendation o Reporting MANAGEMENT/TREATMENT & PREVENTIONS