Efmoroctocog alfa
Pharmaceutical drug From Wikipedia, the free encyclopedia
Efmoroctocog alfa, sold under the brand name Elocta among others, is a medication for the treatment and prophylaxis of bleeding in people with hemophilia A.[5][6][7] Efmoroctocog alfa is a recombinant human coagulation factor VIII, Fc fusion protein (rFVIIIFc).[5] It is produced by recombinant DNA technology in a human embryonic kidney (HEK) cell line.[5][6]
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| Trade names | Elocta, Eloctate |
| Other names | Antihemophilic Factor (Recombinant), FcFusion Protein |
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| Routes of administration | Intravenous |
| Drug class | Antihemorrhagic |
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| Formula | C9736H14863N2591O2855S78 |
| Molar mass | 216390.96 g·mol−1 |
It was approved for medical use in the United States in June 2014,[8] and for use in the European Union in November 2015.[6]
Medical uses
In the United States, efmoroctocog alfa (Eloctate) is indicated for adults and children with Hemophilia A for (1) on-demand treatment and control of bleeding episodes, (2) perioperative management, and (3) routine prophylaxis to prevent or reduce the frequency of bleeding episodes.[9][5]
In the European Union, efmoroctocog alfa (Elocta) is indicated for treatment and prophylaxis of bleeding in people with haemophilia A.[6]
References
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