40S ribosomal protein S4, Y isoform 1

40S ribosomal protein S4, Y isoform 1 is a protein that in humans is encoded by the RPS4Y1 gene.^[4][5][6]

Quick Facts RPS4Y1, Available structures ...

RPS4Y1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 5AJ0, 5FLX, 4D61, 4D5L, 4UJD, 4UJE, 4UJC
Identifiers
Aliases	RPS4Y1, RPS4Y, S4, ribosomal protein S4, Y-linked 1, ribosomal protein S4 Y-linked 1
External IDs	OMIM: 470000; MGI: 98158; HomoloGene: 133576; GeneCards: RPS4Y1; OMA:RPS4Y1 - orthologs
Gene location (Mouse) Chr. X chromosome (mouse)[1] Band X D|X 45.2 cM Start 101,228,547 bp[1] End 101,233,000 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in caput epididymis prostate human penis right lung corpus epididymis rectum trabecular bone urethra synovial joint seminal vesicula Top expressed in epiblast ventricular zone ganglionic eminence uterus zone of skin spleen esophagus thymus embryo urinary bladder More reference expression data BioGPS More reference expression data
Gene ontology Molecular function rRNA binding structural constituent of ribosome RNA binding Cellular component ribosome polysome cytosol nucleus membrane intracellular anatomical structure nucleoplasm cytosolic small ribosomal subunit Biological process SRP-dependent cotranslational protein targeting to membrane viral transcription multicellular organism development nuclear-transcribed mRNA catabolic process, nonsense-mediated decay translational initiation protein biosynthesis rRNA processing Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6192 20102 Ensembl n/a ENSMUSG00000031320 UniProt P22090 P62702 RefSeq (mRNA) NM_001008 NM_009094 RefSeq (protein) NP_000999 NP_033120 Location (UCSC) n/a Chr X: 101.23 – 101.23 Mb PubMed search [2] [3]
Wikidata
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Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ribosomal protein S4, a component of the 40S subunit. Ribosomal protein S4 is the only ribosomal protein known to be encoded by more than one gene, namely this gene, RPS4Y2 and the ribosomal protein S4, X-linked (RPS4X). The 3 isoforms encoded by these genes are not identical, but appear to be functionally equivalent.^[7] Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. It has been suggested that haploinsufficiency of the ribosomal protein S4 genes plays a role in Turner syndrome; however, this hypothesis is controversial.^[4]