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Life Extension Mega Benfotiamine, 250 mg, a Fat-Soluble Form of thiamine, Healthy Metabolism, Ultra-bioavailable Vitamin B1, high Potency, Gluten-Free, Non-GMO, Vegetarian, 120 Capsules

4.6 4.6 out of 5 stars 2,189 ratings
$22.50 $0.19 per Count
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Size: 120 Count (Pack of 1)
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Purchase options and add-ons

Brand Life Extension
Flavor Unflavored
Primary Supplement Type Vitamin B1, Benfotiamine
Unit Count 120.00 Count
Item Form Capsule
Item Weight 0.21 Pounds
Item dimensions L x W x H 2.38 x 2.38 x 4.24 inches
Special Ingredients Thiamine (vitamin B1) (as thiamine HCl), Benfotiamine
Diet Type Vegetarian
Product Benefits Helps support healthy metabolism

About this item

  • Support metabolic health – Benfotiamine is a fat-soluble form of vitamin B1 (thiamine) that supports healthy metabolism. It also helps protect your body’s tissues against oxidative stress and advanced glycation end products (AGEs), which are compounds that accumulate with age.
  • Superior bioavailability – Unlike the water-soluble form, the fat-soluble thiamine (benfotiamine) in our formula easily penetrates cells. It’s been shown to support thiamine levels faster and longer than water-soluble thiamine.
  • Healthy endothelial function – Benfotiamine helps promote a healthy inflammatory response. Taking benfotiamine with thiamine supports healthy endothelial function.
  • Ingredients matter – We use only the finest raw ingredients with the quality and purity you deserve. The majority of our products are non-GMO, gluten-free and manufactured in the USA—and a Certificate of Analysis is available for every one. 
  • Live your healthiest life – We believe the answers to a healthier life are within reach, and that scientific research is the key to getting us there. That’s why so many of our formulas feature specific ingredients and amounts based on scientific studies. 
› See more product details

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180 Count (Pack of 1)
4.6 out of 5 stars (239)
$19.49 ($0.11/Count)

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Life Extension Mega Benfotiamine, 250 mg, a Fat-Soluble Form of thiamine, Healthy Metabolism, Ultra-bioavailable Vitamin B1,
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From the brand

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  2. More than 40 Years of Scientific Innovation

  5. What's in Life Extension supplements?

    We use pure, quality ingredients and clinical dosages.

    Why is it called “Life Extension”?

    Our mission is to help people live their most fulfilling, healthiest life–for as long as possible.

    Where are Life Extension supplements manufactured?

    99% of our products are manufactured in the U.S.A. Our ingredients are sourced worldwide, whether that's wild-caught fish oil for our award-winning omega-3s or responsibly sourced curcumin from Indian co-op farms.

  6. Magnesium
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From the manufacturer

natural 250mg b- control supplements supplement benfothiamine benfotamine vitamins

What Is Mega Benfotiamine?

Mega Benfotiamine contains both the fat-soluble and water-soluble forms of vitamin B1 (thiamine) to support certain aspects of normal metabolic health. Maintaining these levels helps to protect your body against advanced glycation end (AGE) products and oxidative stress.

natural 250mg b- control supplements supplement benfothiamine benfotamine vitamins

Cell energy and beyond

Benfotiamine is a fat-soluble form of vitamin B1 (thiamine) that supports healthy metabolism.

natural 250mg b- control supplements supplement benfothiamine benfotamine vitamins

Say “no” to AGE-ing

Benfotiamine helps protect your body’s tissues against advanced glycation end products (AGEs), which are compounds that accumulate with age.

natural 250mg b- control supplements supplement benfothiamine benfotamine vitamins

Free radical defense

Benfotiamine helps protect your body against oxidative stress.

natural 250mg b- control supplements supplement benfothiamine benfotamine vitamins

All the B benefits

As a form of B1, benfotiamine also delivers the more well-known benefits of B, support for healthy energy, healthy memory and nervous system health.

natural 250mg b- control supplements supplement benfothiamine benfotamine vitamins
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natural 250mg b- control supplements supplement benfothiamine benfotamine vitamins

  • Benfotiamine, a fat-soluble form of vitamin B1 (thiamine), helps support healthy metabolism and protects the body against oxidative stress and glycation end products (AGEs), among other benefits.

  • Thiamine and benfotiamine are the water-soluble and fat-soluble forms of vitamin B1. But benfotiamine is the more absorbable form, and it lasts longer in the body, delivering more B1 benefits.

  • It is perfectly fine to take thiamine and benfotiamine together. In fact, many formulas, including Mega Benfotiamine, offer both forms of vitamin B1 in a single metabolic support supplement.

  • As with many fat-soluble nutrients, such as vitamin D, it’s best to take benfotiamine with food to maximize your body’s ability to use this form of vitamin B1.

Product Description

This formula contains both fat-soluble and water-soluble forms of B1 for better support of healthy metabolism as well as other B1 benefits, such as helping to keep your brain in top form and supporting nerve health. Benfotiamine, a fat-soluble form of vitamin B1 (thiamine), helps protect the body’s tissues against advanced glycation end (AGE) products and oxidative stress. Why do we include it? Benfotiamine is more bioavailable than water-soluble thiamine and can easily penetrate the inside of cells.

Product details

  • Is Discontinued By Manufacturer ‏ : ‎ No
  • Product Dimensions ‏ : ‎ 2.38 x 2.38 x 4.24 inches; 3.36 ounces
  • Item model number ‏ : ‎ 00925
  • Date First Available ‏ : ‎ January 8, 2004
  • Manufacturer ‏ : ‎ Life Extension
  • ASIN ‏ : ‎ B000OSIO9W
  • Country of Origin ‏ : ‎ USA
  • Customer Reviews:
    4.6 4.6 out of 5 stars 2,189 ratings
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Product Safety and Compliance Details

LEGAL DISCLAIMER

Some states prohibit the sale of products intended for weight loss or muscle building to individuals under age 18. Check your local laws prior to purchase.

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Price$22.50-17% $24.89
List: $29.95		-47% $14.49
List: $27.49		$17.32$24.30$49.19
Price Per Unit$0.19 / Count$0.10 / Count$0.24 / Count$0.29 / Count$3.28 / Ounce$0.82 / Count
Delivery
Get it as soon as Wednesday, Mar 19
Get it as soon as Wednesday, Mar 19
Get it as soon as Wednesday, Mar 19
Get it as soon as Wednesday, Mar 19
Get it as soon as Wednesday, Mar 19
Get it as soon as Wednesday, Mar 19
Customer Ratings
4.64.6 out of 5 stars2,189
4.54.5 out of 5 stars38,265
4.64.6 out of 5 stars6,539
4.54.5 out of 5 stars1,429
4.34.3 out of 5 stars41
4.24.2 out of 5 stars41
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Important information

Safety Information

KEEP OUT OF REACH OF CHILDREN DO NOT EXCEED RECOMMENDED DOSE Do not purchase if outer seal is broken or damaged. When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating. To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Ingredients

Thiamine (vitamin B1) (as thiamine HCl) 10 mg Benfotiamine 250 mg Other ingredients: microcrystalline cellulose, vegetable cellulose (capsule), stearic acid, silica, vegetable stearate.

Directions

Take one to four capsule(s) daily with or without food, or as recommended by a healthcare practitioner.

Legal Disclaimer

WARNING: Consuming this product can expose you to chemicals including lead, which are known to the State of California to cause cancer. For more information go to www.P65Warnings.ca.gov/food.

Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.

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Customer reviews

4.6 out of 5 stars
2,189 global ratings

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Customers say

Customers find the nutritional supplement effective for pain relief and preventing bizarre symptoms. They appreciate its high potency, value for money, and ease of swallowing. Many report a boost in energy and clearheadedness after taking it. The vitamin content and sleep quality are also appreciated.

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Pain reliefQualityValue for moneyEase of swallowEnergy levelVitamin contentSleep qualityDiabetes prevention
112 customers mention "Pain relief"91 positive21 negative

Customers report relief from pain with this nutritional supplement. They say it helps with neuropathy, energy, essential tremors, and muscle twitches. Many find it prevents bizarre symptoms and heals diabetic nerve damage. Thiamine is important for supporting the gut-brain axis and preventing eye, nerve, or kidney issues.

"...and the combination of the two supplements has made a difference in my feet feeling better." Read more

"...Thiamine is so important for supporting the gut brain axis. If you got leaky gut, sibo, slow gut motility, you might need more thiamine...." Read more

"...I wish it were cheaper but I can;t do without it. I'ts preventing a lot of bizarre symptoms which I could write a book on, but they come back..." Read more

"...It seems to curb our sweet cravings and improve our digestion." Read more

91 customers mention "Quality"83 positive8 negative

Customers are satisfied with the product's quality. They say it helps relax them and improves blood pressure. The company has a clear purpose for each product, and the potency is high. Some customers find it works well and is a good nootropic supplement.

"...with this company and have always found their products to be high quality with very reasonable prices...." Read more

"Very high potency. You know that cupboard you have of all those vitamins that were amazing the first couple of times then meh? Not these...." Read more

"Easy to swallow or pour into apple sauce. Great quality" Read more

"...It worked beautifully. A some point I ordered a different unknown brand and the pain returned so I went back on this one...." Read more

37 customers mention "Value for money"29 positive8 negative

Customers appreciate the value for money. They say it's worth a try as an alternative to gabapentin or pregabalin.

"...and have always found their products to be high quality with very reasonable prices...." Read more

"great product great price" Read more

"Great price and good quality" Read more

"...I'M GLAD I FOUND IT HERE FOR THE PRICE I GOT IT FOR -- GOOD PRICING FOR THIS SUPPLEMENT." Read more

14 customers mention "Ease of swallow"11 positive3 negative

Customers find the nutritional supplement easy to swallow and take. They mention it's an essential vitamin for diabetics, and manageable.

"Easy to swallow or pour into apple sauce. Great quality" Read more

"...compared to other Benfotiamine options available but pills are easy to swallow and packaging is nice." Read more

"Capsule is easy to swallow. I am not in love with the scent of the pill but there is no taste to it." Read more

"...It could be easier to swallow as it is light and wants to float, but manageable." Read more

12 customers mention "Energy level"12 positive0 negative

Customers like the energy boost and clearheadedness from the nutritional supplement. It helps them feel full for hours, is a great appetite suppressant, and helps them wake up refreshed.

"...pain I was having but on the second day couldn’t believe how solid my energy was and continues 3 weeks later...." Read more

"...item next day delivered I took 2 capsules within 3 hours my energy level was coming back and brain fog gone I feel great actually happy to go to..." Read more

"...then increased to two and finally some improvement in fatigue and have more energy." Read more

"The benfotiamine version works better for me and gives us more energy during the day." Read more

12 customers mention "Vitamin content"12 positive0 negative

Customers appreciate the vitamin content of this nutritional supplement. They mention it's a good diabetes supplement as well as a B vitamin that helps with nerve damage. The supplement includes 10 mg of thiamine, which is fat-soluble.

"...This supplement also includes 10 mg Thiamine.HCl, but according to one health practitioner, it should not exceed 3 mg...." Read more

"Good source for supplements and vitamins...." Read more

"...Make senses, I guess, since it is a thiamine derivative. Maybe it slows down the demyelination. Can't say, but it helps...." Read more

"Excellent form of Vitamin B1 Can't overdoes this stuff and its critical to metabolic energy pathways and body-fat metabolism...." Read more

11 customers mention "Sleep quality"8 positive3 negative

Customers are satisfied with the nutritional supplement's sleep quality. They mention it helps them sleep better, relaxes muscles, and improves fatigue.

"...Also sleeping better. The one side effect however is a very active digestive system. Loose stool’s. Very strong acid smell in le toilet...." Read more

"...not a big improvement then increased to two and finally some improvement in fatigue and have more energy." Read more

"...days and every single time I've ended up with a headache and am excessively tired. If I don't take it I'm fine. I do not recommend this product." Read more

"great product help relax you to sleep as well great for blood pressure" Read more

10 customers mention "Diabetes prevention"10 positive0 negative

Customers like the product for diabetes prevention. They mention it helps with blood sugar issues, diabetic cardiac or retinal damage, neuripathy, metabolic syndrome, and insulin resistance. They haven't had any side effects, but haven't noticed positive results either.

"I BOUGHT THIS SUPPLEMENT TO HELP WITH MY BLOOD SUGAR ISSUES -- I AM VERY PLEASED WITH THE RESULTS, AND HAVE ACTUALLY PURCHASED IT TWICE NOW...." Read more

"Just started. I've only taken this pill for a few days. Haven't had any side effects, but haven't noticed a positive results either...to soon...." Read more

"...No diabetic cardiac or retinal damage. He's been amazing stable over that time, with very slow increases of medication needed to keep his BG in line...." Read more

"...#34;good medicine" in helping reverse metabolic syndrome and insulin resistance." Read more

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Top reviews from the United States

  • chrissj
    5.0 out of 5 stars a very good brand
    Reviewed in the United States on December 3, 2024
    Size: 120 Count (Pack of 1)Verified Purchase
    I am trying out this brand for Benfotiamine as other brands have been upsetting to my stomach. I take it along with Alpha lipoic Acid for nerve issues
    Update:
    I’ve now been taking the Life Extensions Mega Benfotamine for a month. I take it in the morning with my alpha Lipoic acid supplement. Unlike other brands, there isn’t a stomach upset problem for me. I only take one a day and the combination of the two supplements has made a difference in my feet feeling better.
    23 people found this helpful
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  • Sahug
    5.0 out of 5 stars For a high-carb diet
    Reviewed in the United States on January 31, 2025
    Size: 120 Count (Pack of 1)Verified Purchase
    According to Life Extension, it reverses AGI's (advanced glycation end-products), and since thiamine is depleted by a high-carb diet, supplementation is necessary. This supplement also includes 10 mg Thiamine.HCl, but according to one health practitioner, it should not exceed 3 mg. But I think LE has a superb research team that can be trusted.
    10 people found this helpful
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  • Deborah Brill
    5.0 out of 5 stars Great Company, Great Price
    Reviewed in the United States on February 5, 2025
    Size: 120 Count (Pack of 1)Verified Purchase
    I am very impressed with this company and have always found their products to be high quality with very reasonable prices. I personally only started on the Benfotiamine but if it is as effective as their other products then I know it will be a winner.
    2 people found this helpful
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  • jason sisolak
    4.0 out of 5 stars Awesome product. Better at half the dose.
    Reviewed in the United States on March 9, 2025
    Size: 120 Count (Pack of 1)Verified Purchase
    Very high potency. You know that cupboard you have of all those vitamins that were amazing the first couple of times then meh? Not these. I originally purchased to heal some nerve pain I was having but on the second day couldn’t believe how solid my energy was and continues 3 weeks later. My mind especially feels like it turned on for the first time in many years. Also sleeping better. The one side effect however is a very active digestive system. Loose stool’s. Very strong acid smell in le toilet. Didn’t take for a couple of days and gut returned to normal. Definitely looking into befotiamine in a lesser dose since you really can’t split these caps easily.
    One person found this helpful
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  • Gary
    5.0 out of 5 stars Gut brain axis
    Reviewed in the United States on September 7, 2024
    Size: 120 Count (Pack of 1)Verified Purchase
    Different people require different amounts of thiamine. Depending on how many carbs you eat. One of these 3 times per day seems to be the magic number for me. Thiamine is so important for supporting the gut brain axis. If you got leaky gut, sibo, slow gut motility, you might need more thiamine.

    By the way, if you’re interested in supplements that support the gut brain axis I’d be remiss if I didn’t mention Lions Mane mushroom. While it’s not a required nutrient like thiamine, it empowers remarkable healing properties. Lion’s Mane contains compounds such as hericenones and erinacines, that stimulate the production of nerve growth factor (NGF). These compounds support tissue regeneration and may stimulate repair of damaged tissues, including those in the gastrointestinal tract. By promoting NGF, Lion’s Mane strengthens the neural connections between the brain and the gut.

    After nerve damage occurs, NGF helps in the repair and regeneration of damaged nerve cells. It plays a role in recovery from injuries involving the peripheral nervous system. NGF also helps protect against neurotoxicity and oxidative stress, promoting cell survival under harmful conditions.

    How does thiamine relate to Nerve Growth Factor? Some studies suggest that benfotiamine (a fat-soluble form of thiamine), may have a neuroprotective effect, potentially enhancing NGF’s ability to protect and regenerate nerves
    126 people found this helpful
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  • Perriann Nieto
    5.0 out of 5 stars Easy to swallow
    Reviewed in the United States on March 12, 2025
    Size: 120 Count (Pack of 1)Verified Purchase
    Easy to swallow or pour into apple sauce. Great quality
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  • sunflower
    5.0 out of 5 stars Changed From 3 To 5 Stars. Here's Why...
    Reviewed in the United States on December 23, 2017
    Size: 120 Count (Pack of 1)Verified Purchase
    I'll leave my original review from a year ago below but I"m changing my rating from 3 to 5 stars for two big reasons.

    1. My feet are in agony right now. This had been happening to me before I started taking benfotiamine and this was the first brand of it that I tried. It worked beautifully. A some point I ordered a different unknown brand and the pain returned so I went back on this one. Then months passed and again I ordered a cheaper but this time very well known brand in orange and white bottle and immediately the pain returned. I kept telling myself there is no way that it could be from switching brands. But it has become very obvious to me that this is what's happening again. I have no idea why Life Extension's benfotiamine is working but 2 other brands that I've tried didn't. It makes no sense but it is definitely the reality of the situation for me. It seems like this one blunts the effect of blood sugar on nerves and the others didn't.

    2. As you can read in my old review at the end of this one, I was nervous about thiamine increasing cancer risk. After researching that I found out that it is true, if you take a regular dose thiamine supplement. But if you megadose thiamine, such as the amount in one of these pills, the pro cancer effect is actually reversed and thiamine becomes anti cancer.

    I'm about to re order these and return the other brand I've been taking so I can go back to getting some relief, and get my confidence back that my nerves are being protected.

    Original review:
    I have to give 3 stars because I'm very unsure if this product after reading about thiamine's potential to make cancer grow fast. Evidently there are chemo agents designed to block thiamine for that reason. I've been taking this for months, just went through 2 bottles thinking I'm doing the best thing I can do to protect my nerves from the effects of high blood sugar. And although the studies show this works great for that maybe better than anything else and it's been used in Europe as a drug, learning about the cancer aspect scares me.
    Google "benfotiamine cancer" and "thiamine cancer" if you want to read some of the articles I just read about that.

    Update 10/7/2019
    I'm still using this, I've repurchased 9 times. I wish it were cheaper but I can;t do without it. I'ts preventing a lot of bizarre symptoms which I could write a book on, but they come back whenever I start skipping doses.
    280 people found this helpful
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  • CJ
    5.0 out of 5 stars Great supplement
    Reviewed in the United States on December 31, 2024
    Size: 120 Count (Pack of 1)Verified Purchase
    My husband and I have been using this supplement for three months, and we've both found it beneficial. It seems to curb our sweet cravings and improve our digestion.
    18 people found this helpful
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