Adverse drug events

Silvetre, J. S., and Prous, J. (2005). Research on adverse drug events Muscarinic m3 receptor binding affinity could predict the risk of antipsycho tics to induce type 2 diabetes. Meth. Find. Exp. Clin. Pharmacol. 27 289-304. [Pg.174]

Form FDA 3500A Mandatory reporting of adverse drug events by manufacturers Mandatory reporting of adverse device events by manufacturers, importers and device user facilities... [Pg.262]

The first issue lies in the whole realm of the human disease process itself. Many adverse drug events mimic diseases and vice versa. Is an adverse event really an adverse event, or is it merely a natural occurrence of a disease process that is entirely independent of drug exposure The science of drug safety is often complicated by the lack of objective markers of drug toxicity that can systematically separate a disease process from an adverse drug event process [2]. Clinical trials, often viewed as the gold standard to assess efficacy, are simply too limited in scope to answer safety questions in a systematic way. [Pg.652]

To analyze adverse drug events from an informatics framework, six major infrastructure elements must be in place ... [Pg.653]

Landelijke Registratie Evaluatie Bijwerkingen [National Registration and Evaluation of Adverse Drug Events] (Netherlands)... [Pg.142]

All antiarrhythmics can be proarrhythmogenic. Sequential use of more than one agent can result in an adverse drug event. Do not use more than one antiarrhythmic unless absolutely necessary. Electric cardioversion is preferred over a second antiarrhythmic if the initial agent fails. [Pg.18]

Note Critically ill patients (e.g., elderly, organic mental syndrome, pulmonary, cardiac, renal, and/or hepatic impairment) may be at increased risk for adverse drug events. Start with the lowest dose and titrate very carefully. [Pg.74]

Develop a therapeutic plan for patients with chronic asthma that maximizes patient response while minimizing adverse drug events and other drug-related problems. [Pg.209]

Another study randomized patients requiring NSAID prophylaxis to either omeprazole 20 mg daily or ranitidine 150 mg twice daily.19 At 6 months, more patients who received omeprazole (72%) than ranitidine (59%) were in ulcer-free remission (p = 0.004). Omeprazole was also more efficacious in preventing GU recurrence than ranitidine (5.2% versus 16.3% p less than 0.01). Adverse drug events were similar in the two groups. [Pg.278]

Assess and counsel patients on potential adverse drug events and drug interactions. [Pg.280]

Inform patients who are receiving prophylactic therapy on the importance of its use, potential adverse drug events, and the possible alarm symptoms associated with PUD. [Pg.280]

Describe adverse drug events associated with the pharmacotherapy of status epilepticus. [Pg.461]

The goal of therapy is to arrest physical and electroencephalo-graphic evidence of seizures, prevent recurrence of seizures, and minimize adverse drug events. [Pg.461]

Patients who receive antithyroid drugs must be monitored for adverse drug events such as agranulocytosis. [Pg.682]

Further goals include a return to usual activity and prevention of future injury. It is also important to minimize the potential for adverse drug events during treatment. [Pg.902]

Gurwitz JH, Field TS, Harrold LR, et al. Incidence and preventability of adverse drug events among older persons in the ambulatory setting. JAMA. 2003 289(9) 1107-1116. [Pg.1032]

United States General Accounting Office. (2000). "Adverse Drug Events The Magnitude of Health Risk is Uncertain Because of Limited Incidence Data." GAO/HEHS-OO-21. [Pg.226]

Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...