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Immune response positively-charged

Nakanishi, T. Kunisawa, J. Hayashi, A. Tsutsumi, Y. Kubo, K. Nakagawa, S. Nakanishi, M. Tanaka, K. Mayumi, T. Positively charged liposome functions as an efficient immunoadjuvant in inducing cell-mediated immune response to soluble proteins. J. Controlled Rel. 1999, 61, 233-240. [Pg.3927]

In contrast, the positive charge of chitosan induced by deacetylation of chitin, a natural polysaccharide found in crab shells and many shellfish, is supposed to be correlated with cell attachment increase, inflammation reduction, and biocompatibility enhancement. Chitosan will not trigger an immune response and promote cell adhesion and spreading such as osteoblasts [38], keratinocytes, and neuronal cells. It can also be covalently bonded to adhesion peptides such as the RGD to improve cell adhesion [39]. [Pg.287]

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Charge response

Immune response

Immune response positively-charged liposomes

Positive charge

Positively charged

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