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Kinetic dynamic

Dynamic instability of microtubules, MICROTUBULE ASSEMBLY KINETICS Dynamic light scattering,... [Pg.738]

Van Boxtel CJ, Holford NHG, Danhof M, editors. The in vivo study of drug action. Principles and applications of kinetic-dynamic modelling. Amsterdam Elsevier 1992. [Pg.179]

The rate of chemical reactions can be described at two levels dynamics and kinetics. Dynamics is the description of the rate of transformation for individual molecules. The molecule has a well-defined energy, it may even start in a well-defined quantum state. There is no temperature. Temperature is a property of a large number of molecules, not individual molecules. [Pg.16]

Greenblatt, D J., Harmatz, J.S., Gonthro, T.A., et a/. Distinguishing a benzodiazepine agonist ( triazolam) from a nonagonist anxiolytic (buspirone) by electroencephalography kinetic-dynamic studies. CHn. Pharmacol. Ther. 56, 100— 111, 1994. [Pg.345]

Although, relevant information about ferrous hemeproteins kinetics, dynamics and ligand photodissociation pathways has been obtain, less is known about ferric hemeproteins photophysic processes. Recent studies performed with Hbl-CN and Mb-CN at ultrafast time scale, have suggested that some of the transients intermediaries observed after ferrous complexes ligand photodissociation are observed in ferric Mb and Hbl [7], However, time-resolved infrared data shows that the complex remained six coordinated after photoexcitation. In this work we present ultrafast data on ferric Hbl-NO, HM-N3, HM-H2S and metHbl complexes that suggest a mechanism for the photoinduced reduction of Hbl species. [Pg.395]

This monograph deals with kinetics, not with dynamics. Dynamics, the local (coupled) motion of lattice constituents (or structure elements) due to their thermal energy is the prerequisite of solid state kinetics. Dynamics can explain the nature and magnitude of rate constants and transport coefficients from a fundamental point of view. Kinetics, on the other hand, deal with the course of processes, expressed in terms of concentration and structure, in space and time. The formal treatment of kinetics is basically phenomenological, but it often needs detailed atomistic modeling in order to construct an appropriate formal frame (e.g., the partial differential equations in space and time). [Pg.5]

Brezonik, P.L., Principles of linear free energy and structure-activity relationships and their applications to the fate of chemicals in aquatic systems, in Chemical Kinetic Dynamic in Aquatic Systems, Lewis Publishers, Boca Raton, FL, 1994, pp. 113-143. [Pg.434]

Table 3 Options for Pharmacodynamic Endpoints in Kinetic-Dynamic Studies of GABA-Benzodiazepine Agonist Drugs... Table 3 Options for Pharmacodynamic Endpoints in Kinetic-Dynamic Studies of GABA-Benzodiazepine Agonist Drugs...
The general methods of preparation of phosphole oxides, sulfides, and selenides have been described in Section 3.15.5.1.3. A tentative resolution of chiral phosphole 76 under kinetic dynamic resolution conditions is noteworthy, despite only low enantioselectivities (10-20%) having been obtained (Scheme 20) <2004TA3519>. [Pg.1073]

Another burst of activity in free radical research occurred in the 1960s and 1970s, after several reports of anomalous intensities in the EPR spectra of photochemically or radiolytically produced radicals, and in the NMR spectra of the products from free radical reactions in solution." " These so-called chemically induced magnetic spin polarization (CIDNP and CIDEP) phenomena provided a wealth of mechanistic, kinetic, dynamic, and structural information and were a cornerstone of carbon-centered free radical research for the better part of three decades. The umbrella term for this area of research is spin chemistry, which is defined as the chemistry of spin-selective processes. [Pg.4]

Effect on kinetics/dynamics Risk factors for side effects ... [Pg.161]

Kinetics of Interface Reactions, M. Grunze, H.J. Kreuzer. Eds., Springer (1986). (Proceedings of a workshop, kinetics, dynamics versus thermodynamics.)... [Pg.149]

W. H. Weinberg, Kinetics of Surface Reactions , Advances in Gas-Phase Photochemistry and Kinetics Dynamics of Gas-Surface Interactions, Eds. C. T. Rettner and M. N. R. Ashfold (The Royal Society of Chemistry, North Yorkshire, Great Britain, 1991) pp. 171-219. [Pg.481]

Part of the answer to the arguments has been the recent measurement of the NP values of specihc minerals (Jambor et al., 2002), and the replacement, by some regulatory agencies, of the absolute value of NNP, adopting in its place the ratio of NP/AP for environmental assessments. Like other environmental parameters, the ratio deemed to be appropriate is different in various jurisdictions. Whether NNP values or NP/AP ratios are used, however, commonly they are but one part of a more comprehensive, site-specific environmental evaluation that includes kinetic (dynamic) laboratory tests. [Pg.4725]

Designing chemicals that are less toxic is one of the principles of green chemistry and the focus of this chapter is to present an expansion of this principle into a comprehensive approach for designing safer chemicals that can be used in the classroom. The same tools of chemistry used to examine structure, kinetics, dynamics and mechanisms that have revolutionized the electronics, transportation, and communication industries can also be used to design minimal hazard into chemical products. Minimized hazard needs to be understood as a performance criterion in the design of safer chemicals. The existence of hazard should be recognized as a design flaw. [Pg.120]

Tullock W, Scott V, Smith DA, Phillips L, Cook DR. Kinetics/dynamics of 51W89 in liver transplant patients and in healthy patients. Anesthesiology 1994 81 A1076. [Pg.794]

Physiochemical constraints, e.g. - energetics, kinetics, dynamic behavior... [Pg.224]

Process Reaction systems (Chemical Kinetics) Dynamics... [Pg.4]

R. Wills, A kinetic/dynamic perspective of a peptide and protein GRF and rHuIFN-alpha-2a in Peptides, Peptoids, and Proteins (Eds. P. Garzone, W. Colburn, M. Mokotoff), Harvey Whitney Books, Cincinnati, OH, 1991, pp. 117-127. [Pg.170]

Sanathanan, L. P, Random effects modehng in population kinetic/dynamic analysis, Drug Inf J., 25 307-318, 1991. [Pg.355]

Some properties of a drug or its class may make it insensitive to ethnic factors. This will make it easier for extrapolation to different regions and reduce the need for bridging clinical data. Properties that make it susceptible to ethnic influences see likelihood Ethnic Sensitive/Insensitive in Table 29.1 will require bridging studies, sometimes of pharmaco-kinetics/dynamics studies or safety and efficacy either or both. [Pg.357]

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A dynamic kinetic resolution

Alcohols, dynamic kinetic resolution

Amines dynamic kinetic resolution

Applications dynamic kinetic resolution

Applications of Dynamic Kinetic Resolution

Asymmetric catalysis dynamic kinetic resolution

Asymmetric transformation kinetic resolution Dynamic

Aziridine, dynamic kinetic asymmetric

Azlactones, dynamic kinetic resolution

Biocatalysis dynamic kinetic resolution

Biotransformations dynamic kinetic resolution

Candida antarctica lipase dynamic kinetic resolution

Carboxylic esters, dynamic kinetic

Carboxylic esters, dynamic kinetic resolution

Catalytic Kinetics and Dynamics

Chemical kinetics dynamics

Chiral amines dynamic kinetic resolution

Collision dynamics simple kinetic theory

Cyclohexanone dynamic kinetic resolution

DYKAT diols, dynamic kinetic

Dehydrogenases dynamic reductive kinetic resolution

Diastereoselective dynamic kinetic resolution

Diastereoselective dynamic kinetic resolution process

Diketone dynamic kinetic resolution

Diols dynamic kinetic resolution

Dynamic Kinetic Resolution Through Reduction

Dynamic Kinetic Resolution and Deracemization

Dynamic Kinetic Resolution and Desymmetrization

Dynamic Kinetic Resolution of Amines and Amino Acids

Dynamic Kinetic Resolution of Racemic Alcohols

Dynamic Kinetic Resolution of Racemic Amines

Dynamic Kinetic Resolution of Racemic Azlactones

Dynamic Kinetic Resolution of Secondary Alcohols

Dynamic Kinetic Resolutions Based on Reduction Processes

Dynamic Kinetic Resolutions by Enzymes Coupled with Metal Catalysts

Dynamic Models for Transient Operation Techniques (Nonstationary Kinetics)

Dynamic Versions of Kinetic Monte Carlo

Dynamic biochemistry enzyme kinetics

Dynamic catalysis transient kinetics

Dynamic combinatorial libraries kinetic

Dynamic equilibrium, kinetics

Dynamic kinetic asymmetric

Dynamic kinetic asymmetric 1.5- diols

Dynamic kinetic asymmetric amines

Dynamic kinetic asymmetric carbonate

Dynamic kinetic asymmetric catalysts

Dynamic kinetic asymmetric enantioselectivity

Dynamic kinetic asymmetric enzymes

Dynamic kinetic asymmetric esters

Dynamic kinetic asymmetric hydrogenation

Dynamic kinetic asymmetric metal-catalyzed racemization

Dynamic kinetic asymmetric process

Dynamic kinetic asymmetric racemic alcohols

Dynamic kinetic asymmetric racemic amines

Dynamic kinetic asymmetric racemic desymmetrization

Dynamic kinetic asymmetric racemization

Dynamic kinetic asymmetric ruthenium catalyst

Dynamic kinetic asymmetric synthesis

Dynamic kinetic asymmetric transformation

Dynamic kinetic asymmetric transformation DYKAT)

Dynamic kinetic bioreduction

Dynamic kinetic enantioselective

Dynamic kinetic enantioselective hydroamination

Dynamic kinetic models

Dynamic kinetic protonation

Dynamic kinetic resolution

Dynamic kinetic resolution (DKR

Dynamic kinetic resolution asymmetric transfer hydrogenation

Dynamic kinetic resolution carbanion

Dynamic kinetic resolution chemoenzymatic

Dynamic kinetic resolution chiral compounds

Dynamic kinetic resolution enzymatic stereoselective synthesis

Dynamic kinetic resolution hydrogenation

Dynamic kinetic resolution hydrolases

Dynamic kinetic resolution ketone ketones

Dynamic kinetic resolution methodology

Dynamic kinetic resolution of racemic ketones through asymmetric reduction

Dynamic kinetic resolution processes

Dynamic kinetic resolution reaction scheme

Dynamic kinetic resolution reductive amination

Dynamic kinetic resolution rotation

Dynamic kinetic resolution stereoselection

Dynamic kinetic resolution transaminases

Dynamic kinetic resolution using hydrolytic enzymes

Dynamic kinetic resolution, keto

Dynamic kinetic resolution, keto esters

Dynamic kinetic resolutions DKRs)

Dynamic kinetic stability

Dynamic kinetically resolved

Dynamic reductive kinetic resolution

Dynamic structure, reaction kinetics

Dynamic structure, reaction kinetics studies

Dynamic) Kinetic Resolution of Racemic Compounds

E dynamic kinetic resolution

Elastic collision dynamics kinetic energy

Energetics, Kinetics and Dynamics of Quadruplex Folding

Epoxides dynamic kinetic resolution

Extracting Kinetic and Thermodynamic Properties of Local Unfolding Dynamics

Hydrolases, dynamic kinetic resolution alcohols

Kinetic Monte Carlo simulation dynamic processes

Kinetic Parameters and Dynamics

Kinetic dynamic, racemic monomers

Kinetic energy dynamics

Kinetic modeling dynamic flux analysis

Kinetic modeling dynamic model

Kinetic resolutions dynamic resolution

Kinetic studies, dynamic method

Kinetic theory dynamics

Kinetics Brownian dynamics

Kinetics and Dynamics. Local Equilibrium

Kinetics and dynamics

Kinetics dynamic kinetic resolution

Lipase-based dynamic kinetic resolution

Lipases dynamic kinetic resolution

Mathematical Modeling of Dynamic Process Kinetics

Molecular dynamics kinetic cycle

Molecular dynamics simulations kinetic theory

Monte Carlo kinetic, dynamic

Nitrilases dynamic kinetic resolution

Norsertraline, dynamic kinetic

Norsertraline, dynamic kinetic resolution

Oscillatory kinetics and nonlinear dynamics

Oxazolones, dynamic kinetic resolution

Production of Amino Acids by (Dynamic) Kinetic Resolution

Propargyl dynamic kinetic asymmetric transformation

Racemates resolution, dynamic kinetic

Racemic compounds dynamic kinetic resolution

Racemic dynamic kinetic resolution

Racemizable Acyl Donors for Enzymatic Dynamic Kinetic Resolution

Reaction kinetics and dynamic

Reactions Kinetics, Dynamics, and Equilibrium

Reactions dynamic kinetic resolution

Recombination Kinetics and Spin Dynamics

Reduction dynamic kinetic resolution

Reductions involving dynamic kinetic

Resolution, dynamic kinetic enzymatic

Resolution, dynamic kinetic industrial

Resolution, dynamic kinetic industrial scale

Resolution, dynamic kinetic lipase-catalyzed

Roxifiban, dynamic kinetic resolution

Ru-catalyzed hydrogenation of racemic 2-substituted aldehydes via dynamic kinetic resolution

Ruthenium catalysts alcohol racemization, dynamic kinetic

Ruthenium catalysts dynamic kinetic resolution

Ruthenium-catalyzed dynamic kinetic

Ruthenium-catalyzed dynamic kinetic resolution

Secondary alcohols, dynamic kinetic

Secondary alcohols, dynamic kinetic resolution

Slow dynamical systems and chemical kinetics equations

Stereogenic center dynamic kinetic resolution

Stereoselective dynamic kinetic resolution

Stereoselectivity dynamic kinetic resolution

The Connection between dynamics and kinetics

The Dynamics of Electron Transfer (Kinetics and Thermodynamics)

Theory of Transient State Kinetics and Dynamics

Thioesters dynamic kinetic resolution

Transaminases, dynamic kinetic

Zero kinetic energy condition dynamics

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