Your search for: 'author:("Yin, Xiang")' has returned 4 results. (0.011s) Save search

Authors: Yin, Xiang | Li, Bin | Li, Dongdong | Zhang, Yonglong | Zhu, Junwu

Article Type: Research Article

Abstract: In this paper, we study the problem of coalition formation for task allocation in agent networks, in particular, we consider the situation where the profits of tasks are elapsed with time. A novel distributed algorithm is proposed, by designing a “quit-to-choose” mechanism, agents can make decisions with more rationality, so that more coalitions can be formed and the overall utility of the system is improved. Our algorithm is decentralized and it only requires local information about other agents. In addition, the complexity of the proposed algorithm is analyzed to show that it is easy to be implemented. We then conduct …a variety of experiments in four different networks to verify the performance of the proposed algorithm, the results demonstrate that compared with the greedy mechanism, our algorithm can highly improve the system profit. Show more

Keywords: Multi-agent systems, coalition formation, agent networks, task allocation, discount factor

DOI: 10.3233/IFS-151746

Citation: Journal of Intelligent & Fuzzy Systems, vol. 30, no. 1, pp. 197-210, 2016

Authors: Yin, Xiang | Guan, Li | Li, Bing | Huang, Qing | Lin, Huijie

Article Type: Research Article

Abstract: This article has been retracted. A retraction notice can be found at https://doi.org/10.3233/JIFS-219433 .

DOI: 10.3233/JIFS-236323

Citation: Journal of Intelligent & Fuzzy Systems, vol. 46, no. 2, pp. 3491-3503, 2024

Authors: Yin, Ping | Wang, Shuang | Wei, Yafen | Wang, Xu | Zhang, Jingdian | Yin, Xiang | Feng, Jiachun | Zhu, Mingqin

Article Type: Research Article

Abstract: Inflammation resolution is regulated by specialized pro-resolving lipid mediators (SPMs) and the levels of SPMs are found decreased in Alzheimer’s disease (AD) brain. We have previously found that one of the SPMs, Maresin1 (MaR1), improved neuronal survival and increase microglial phagocytosis of amyloid-β 1-42 (Aβ42 ); however, the mechanisms underlying the protective mechanism remain further investigation. We aim to investigate the effects of MaR1 on microglial chemotaxis and activation in this study. Both indirect and direct primary neuron and microglia co-culture system was used in this study. Our results showed MaR1 downregulated the increased microglial chemotaxis induced by Aβ42 . …The microglial inactivation marker CD200R was downregulated by Aβ42 and upregulated by MaR1. Pro-inflammatory cytokines secretion such as tumor necrosis factor (TNF)-α were increased by Aβ42 and these changes were revised by MaR1 treatment. In addition, the levels of chemokine monocyte chemoattractant protein (MCP)-1 were increased while the levels of anti-inflammatory factor IL-10 secretion were decreased by Aβ42 , and these changes were abolished by MaR1 treatment. Moreover, by proteomics analysis, we identified cell signaling pathways affected by MaR1 were not only limited to inflammation-related pathways such as P38, but also in pathways involved in cell survival, autophagy, axon formation, and apoptosis, including PI3K/AKT, mTOR, ERK, caspase3, Cdc42, and p75NTR. In conclusion, MaR1 promoted inflammation resolution by inhibiting chemotaxis and regulating activation of microglia. MaR1 played a neuroprotective role by affecting cell signaling pathways involving inflammation, cell survival, autophagy, axon formation, and apoptosis inhibition. Show more

Keywords: Alzheimer’s disease, chemotaxis, Maresin1, microglia, proteomics, resolution of inflammation

DOI: 10.3233/JAD-190682

Citation: Journal of Alzheimer's Disease, vol. 73, no. 2, pp. 503-515, 2020

Authors: Liang, Hongtao | Yin, Xiang | Chen, Tian | Zhang, Yan | Zhang, Qin | Lin, Jie | Yin, Huan | Tang, Jinghua | He, Yingyi | Xia, Ping | Zhu, Yongping | Li, Haihua | Mo, Yongbiao | Li, Yongyong | Wang, Ying | Yang, Xiao | Hu, Zicheng

Article Type: Research Article

Abstract: Background: Cognitive impairment is commonly seen after acute ischemic stroke (AIS). Sedentary behaviors increase the risk of dementia among community dwelling population. Objective: This study aims to investigate the association of sedentary behaviors with poststroke cognitive impairment among older adults with minor AIS. Methods: This cohort study recruited 594 older subjects with minor AIS from three hospitals in China during February 1, 2016, and December 31, 2018. Participants were followed up for two years and the sedentary time per day was self-reported at the end of follow-up. Cognitive functions were assessed by Mini-Mental State Examination (MMSE). Participants were categorized into …the high and low sedentary time group according to the median sedentary time of the participants. Results: At two years of follow-up, the long sedentary time group had significantly lower MMSE scores than the short sedentary time group [median, (IQR): 21 (18 to 25) versus 22 (18 to 25), p  = 0.368]. The long sedentary time group had a higher speed of cognitive decline than the short sedentary time group. Excessive sedentary time was associated with a higher risk of longitudinal cognitive decline (OR: 2.267, 95% CI: 1.594 to 3.225), adjusting for age, sex, education, body mass index, APOE genotype, comorbidities, symptoms of depression, anxiety, and insomnia, baseline MMSE scores and National Institute of Health Stroke Scale scores, cognitive therapy, and TOAST ischemic stroke subtypes. Conclusions: This study identified a possible link between sedentary behaviors and longitudinal cognitive decline among older patients with minor AIS, suggesting that reducing sedentary time might be helpful for preventing poststroke dementia. Show more

Keywords: Acute ischemic stroke, Alzheimer’s disease, cognitive impairment, older adults, sedentary behavior

DOI: 10.3233/JAD-230008

Citation: Journal of Alzheimer's Disease, vol. 96, no. 1, pp. 173-181, 2023