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Dietary intake affects blood levels of α-carotene, which in one study was associated with significantly lower risk of PREMATURE death. |
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{{Short description|Previtamin}}
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| ImageFile = Alpha-carotene.svg
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| Name =
| IUPACName = (6′''R'')-β,ε-Carotene
| SystematicName = 1,3,3-Trimethyl-2-<nowiki/>{(1''E'',3''E'',5''E'',7''E'',9''E'',11''E'',13''E'',15''E'',17''E'')-3,7,12,16-tetramethyl-18-[(1''R'')-2,6,6-trimethylcyclohex-2-en-1-yl]octadeca-1,3,5,7,9,11,13,15,17-nonaen-1-yl}cyclohex-1-ene
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'''α-Carotene''' (''alpha''-carotene) is a form of [[carotene]] with a β-[[ionone]] ring at one end and an α-[[ionone]] ring at the opposite end. It is the second most common form of [[carotene]].
==Human physiology==
* {{cite news |vauthors=Nordqvist C|date=November 22, 2010 |title=Those With High Alpha-Carotene Blood Levels Live Much Longer |work=Medical News Today |url=http://www.medicalnewstoday.com/articles/208965.php}}</ref><ref>[http://www.tuftshealthletter.com/ShowArticle.aspx?rowId=928 ''Alpha-carotene Linked to Lower Mortality Rates'' ] {{Webarchive|url=https://web.archive.org/web/20120513164242/http://www.tuftshealthletter.com/ShowArticle.aspx?RowID=928 |date=May 13, 2012 }}, Tufts Health and Nutrition Letter, March 2011</ref>
▲ {{Expand section|date=February 2013}}
▲Dietary intake affects blood levels of α-carotene, which in one study was associated with significantly lower risk of premature death.<ref name=Li2010>{{cite journal |author=Li C, Ford ES, Zhao G, Balluz LS, Giles WH, Liu S |title=Serum α-carotene concentrations and risk of death among US Adults: the Third National Health and Nutrition Examination Survey Follow-up Study |journal=Arch. Intern. Med. |volume=171 |issue=6 |pages=507–15 |date=March 2011 |pmid=21098341 |doi=10.1001/archinternmed.2010.440 |url=http://archinte.ama-assn.org/cgi/content/full/archinternmed.2010.440v1 |laysummary=[http://www.medicalnewstoday.com/articles/208965.php Those With High Alpha-Carotene Blood Levels Live Much Longer] |laysource=Medical News Today |laydate=22 November 2010}}</ref><ref>[http://www.tuftshealthletter.com/ShowArticle.aspx?rowId=928 ''Alpha-carotene Linked to Lower Mortality Rates'' ], Tufts Health and Nutrition Letter, March 2011</ref>
==Dietary sources==
The following vegetables are rich in alpha-carotene:<ref name=Li2010/>
* Yellow-orange vegetables
* Dark-green vegetables
==Research==
A 2018 meta-analysis found that both dietary and [[Blood test|circulating]] α-carotene are associated with a lower risk of all-cause [[Mortality rate|mortality]]. The highest circulating α-carotene category, compared to the lowest, correlated with a 32% reduction in the risk of all-cause mortality, while increased dietary α-carotene intake was linked to a 21% decrease in the risk of all-cause mortality.<ref name="pmid30239557">{{cite journal| vauthors=Jayedi A, Rashidy-Pour A, Parohan M, Zargar MS, Shab-Bidar S| title=Dietary Antioxidants, Circulating Antioxidant Concentrations, Total Antioxidant Capacity, and Risk of All-Cause Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Observational Studies. | journal=Adv Nutr | year= 2018 | volume= 9 | issue= 6 | pages= 701–716 | pmid=30239557 | doi=10.1093/advances/nmy040 | pmc=6247336 }} </ref>
==References==
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{{Carotenoids}}
{{Vitamin}}
{{Terpenoids}}
{{DEFAULTSORT:Carotene, Alpha-}}
[[Category:Carotenoids]]
[[Category:Tetraterpenes]]
[[Category:Cyclohexenes]]
[[Category:Vitamin A]]
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