Melanin: Difference between revisions

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As with peoples having migrated northward, those with light skin migrating toward the equator acclimatize to the much stronger solar radiation. Nature selects for less melanin when ultraviolet radiation is weak. Most people's skin darkens when exposed to UV light, giving them more protection when it is needed. This is the physiological purpose of [[sun tanning]]. Dark-skinned people, who produce more skin-protecting eumelanin, have a greater protection against [[sunburn]] and the development of melanoma, a potentially deadly form of skin cancer, as well as other health problems related to exposure to strong [[solar radiation]], including the [[photodegradation]] of certain [[vitamin]]s such as [[riboflavin]]s, [[carotenoid]]s, [[tocopherol]], and [[folate]].<ref>{{Cite journal|last1=Jablonski|first1=Nina G.|last2=Chaplin|first2=George|date=11 May 2010|title=Human skin pigmentation as an adaptation to UV radiation|journal=Proceedings of the National Academy of Sciences|volume=107|issue=Supplement 2|pages=8962–8968|doi=10.1073/pnas.0914628107|pmid=20445093|pmc=3024016|bibcode=2010PNAS..107.8962J|doi-access=free}}</ref>
 
Melanin in the eyes, in the [[Iris (anatomy)|iris]] and [[choroid]], helps protect from [[ultraviolet]] and [[high-energy visible light|high-frequency visible light]]; people with [[Eye color|gray, blue, green and greengrey eyes]] are more at risk of sun-related eye problems. <!--
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--> Furthermore, the ocular lens yellows with age, providing added protection. However, the lens also becomes more rigid with age, losing most of its [[accommodation (eye)|accommodation]]—the ability to change shape to focus from far to near—a detriment due probably to [[protein]] crosslinking caused by UV exposure.