Wikipedia:Reference desk/Science: Difference between revisions

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== Protein architecture, motif, domain, fold, topology. ==
 
I'm taking a 4th level biochemistry class titled Protein structure and function and, though I already learned them intro biochem courses, the way the materials are covered is much more detailed. I don't really understand the following: architecture, motif, domain, fold, topology (used in a different sense instead of the more common definition of how the transmembrane protein is embedded). Many of these terms are used interchangeable and I don't have a clear idea of the true definition of each. For example, ItI saw a/b domain being also referred to as a/b architecture. Also, it seems that Greek key motif is also called a Greek key domain, which can also be said to be an architecture. Also, fold and motif seem to be complete synonyms. I'm really confused. Please clarify with clear examples. (PLEASE DON'T JUST REDIRECT ME TO LINKS HAVING GENERAL DEFINITIONS OF EACH, BECAUSE I ALREADY CHECKED MANY OF THEM OUT) <span style="font-size: smaller;" class="autosigned">—Preceding [[Wikipedia:Signatures|unsigned]] comment added by [[Special:Contributions/142.58.129.94|142.58.129.94]] ([[User talk:142.58.129.94|talk]]) 21:43, 5 March 2010 (UTC)</span><!-- Template:UnsignedIP --> <!--Autosigned by SineBot-->
 
== Positive and negative features of CATH and SCOP ==