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Occasionally, patients have developed [[cholestatic hepatitis]] or [[delirium]]. Accidental intravenous overdosage in an infant caused severe heart block, resulting in residual encephalopathy.<ref>{{ cite pmid | 16506357 }}</ref> <ref>{{ cite book | author = Baselt, R. | title = Disposition of Toxic Drugs and Chemicals in Man | edition = 8th | publisher = Biomedical Publications | location = Foster City, CA | year = 2008 | pages = 132–133 }}</ref>
A 2012 study found the drug may increase the risk of death, especially in those with heart problems, compared with those on other antibiotics such as amoxicillin or no antibiotic.<ref>http://news.yahoo.com/common-antibiotic-boosts-death-risk-study-213206509.html</ref>
== Mechanism of action ==
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