Ezio is an Italian masculine name, originating from the Latin name Aetius.
It may refer to:
- Ezio, opera libretto by Metastasio, first officially set to music by Pietro Auletta and premièred in the Teatro delle Dame, Rome, on December 26, 1728; an unauthorized setting by Nicola Porpora had already been premièred a month earlier (November 20) in Venice. Other notable settings include:
- Ezio (Handel), King's Theatre, London 1732
- Ezio (Mysliveček) (1775), Naples
- Ezio (Mysliveček) (1777), Munich – completely new music
- Ezio (Gluck), Prague 1750, revised Vienna 1763
- Ezio (Traetta) by Tommaso Traetta, Teatro delle Dame, Rome, 1757
- Ezio (Latilla), Naples 1758
- Ezio (band), a band from Cambridge, England
- Ezio Lunedei, the lead singer of Ezio
- Ezio Gamba (born 1958), an Italian judoka
- Ezio Auditore da Firenze, the protagonist of Ubisoft's Assassin's Creed II, Assassin's Creed Brotherhood and Assassin's Creed Revelations
- Ezio (security), a security solution range for online banking and shopping from Gemalto
- EZ-IO, an intraosseous infusion drill by Vidacare
- Ezio (Flavius Aetius), character from Verdi's Attila (opera)