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==Interactions==
==Interactions==
TRIB3 has been shown to [[Protein-protein interaction|interact]] with [[CSNK2B]],<ref name=pmid18276110>{{cite journal |last=Zhou |first=Ying |authorlink= |coauthors=Li Lu, Liu Qiongming, Xing Guichun, Kuai Xuezhang, Sun Jing, Yin Xiushan, Wang Jian, Zhang Lingqiang, He Fuchu |year=[[2008]]|month=May. |title=E3 ubiquitin ligase SIAH1 mediates ubiquitination and degradation of TRB3 |journal=Cell. Signal. |volume=20 |issue=5 |pages=942–8 |publisher= |location = England| issn = 0898-6568| pmid = 18276110 |doi = 10.1016/j.cellsig.2008.01.010 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> [[TIAF1]],<ref name=pmid18276110/> [[RELA]],<ref name=pmid12736262>{{cite journal |last=Wu |first=Min |authorlink= |coauthors=Xu Liang-Guo, Zhai Zhonghe, Shu Hong-Bing |year=[[2003]]|month=Jul. |title=SINK is a p65-interacting negative regulator of NF-kappaB-dependent transcription |journal=J. Biol. Chem. |volume=278 |issue=29 |pages=27072–9 |publisher= |location = United States| issn = 0021-9258| pmid = 12736262 |doi = 10.1074/jbc.M209814200 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> [[MCM3AP]],<ref name=pmid18276110/> [[ATF5]],<ref name=pmid18276110/> [[Granulin]],<ref name=pmid18276110/> [[ATF4]],<ref name=pmid18276110/><ref name=pmid12743605>{{cite journal |last=Bowers |first=Alex J |authorlink= |coauthors=Scully Sheila, Boylan John F |year=[[2003]]|month=May. |title=SKIP3, a novel Drosophila tribbles ortholog, is overexpressed in human tumors and is regulated by hypoxia |journal=Oncogene |volume=22 |issue=18 |pages=2823–35 |publisher= |location = England| issn = 0950-9232| pmid = 12743605 |doi = 10.1038/sj.onc.1206367 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> [[AKT1]],<ref name=pmid12791994>{{cite journal |last=Du |first=Keyong |authorlink= |coauthors=Herzig Stephan, Kulkarni Rohit N, Montminy Marc |year=[[2003]]|month=Jun. |title=TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver |journal=[[Science (journal)|Science]] |volume=300 |issue=5625 |pages=1574–7 |publisher= |location = United States| issn = | pmid = 12791994 |doi = 10.1126/science.1079817 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> [[Fibronectin]]<ref name=pmid18276110/> and [[SIAH1]].<ref name=pmid18276110/>
TRIB3 has been shown to [[Protein-protein interaction|interact]] with [[CSNK2B]],<ref name=pmid18276110>{{cite journal |last=Zhou |first=Ying |authorlink= |coauthors=Li Lu, Liu Qiongming, Xing Guichun, Kuai Xuezhang, Sun Jing, Yin Xiushan, Wang Jian, Zhang Lingqiang, He Fuchu |year=2008|month=May. |title=E3 ubiquitin ligase SIAH1 mediates ubiquitination and degradation of TRB3 |journal=Cell. Signal. |volume=20 |issue=5 |pages=942–8 |publisher= |location = England| issn = 0898-6568| pmid = 18276110 |doi = 10.1016/j.cellsig.2008.01.010 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> [[TIAF1]],<ref name=pmid18276110/> [[RELA]],<ref name=pmid12736262>{{cite journal |last=Wu |first=Min |authorlink= |coauthors=Xu Liang-Guo, Zhai Zhonghe, Shu Hong-Bing |year=2003|month=Jul. |title=SINK is a p65-interacting negative regulator of NF-kappaB-dependent transcription |journal=J. Biol. Chem. |volume=278 |issue=29 |pages=27072–9 |publisher= |location = United States| issn = 0021-9258| pmid = 12736262 |doi = 10.1074/jbc.M209814200 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> [[MCM3AP]],<ref name=pmid18276110/> [[ATF5]],<ref name=pmid18276110/> [[Granulin]],<ref name=pmid18276110/> [[ATF4]],<ref name=pmid18276110/><ref name=pmid12743605>{{cite journal |last=Bowers |first=Alex J |authorlink= |coauthors=Scully Sheila, Boylan John F |year=2003|month=May. |title=SKIP3, a novel Drosophila tribbles ortholog, is overexpressed in human tumors and is regulated by hypoxia |journal=Oncogene |volume=22 |issue=18 |pages=2823–35 |publisher= |location = England| issn = 0950-9232| pmid = 12743605 |doi = 10.1038/sj.onc.1206367 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> [[AKT1]],<ref name=pmid12791994>{{cite journal |last=Du |first=Keyong |authorlink= |coauthors=Herzig Stephan, Kulkarni Rohit N, Montminy Marc |year=2003|month=Jun. |title=TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver |journal=[[Science (journal)|Science]] |volume=300 |issue=5625 |pages=1574–7 |publisher= |location = United States| issn = | pmid = 12791994 |doi = 10.1126/science.1079817 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> [[Fibronectin]]<ref name=pmid18276110/> and [[SIAH1]].<ref name=pmid18276110/>


==References==
==References==

Revision as of 04:07, 27 July 2012

Template:PBB Tribbles homolog 3 is a protein that in humans is encoded by the TRIB3 gene.[1][2][3]

Template:PBB Summary

Interactions

TRIB3 has been shown to interact with CSNK2B,[4] TIAF1,[4] RELA,[5] MCM3AP,[4] ATF5,[4] Granulin,[4] ATF4,[4][6] AKT1,[1] Fibronectin[4] and SIAH1.[4]

References

  1. ^ a b Du K, Herzig S, Kulkarni RN, Montminy M (2003). "TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver". Science. 300 (5625): 1574–7. doi:10.1126/science.1079817. PMID 12791994. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link) Cite error: The named reference "pmid12791994" was defined multiple times with different content (see the help page).
  2. ^ Hegedus Z, Czibula A, Kiss-Toth E (2006). "Tribbles: novel regulators of cell function; evolutionary aspects". Cell Mol Life Sci. 63 (14): 1632–41. doi:10.1007/s00018-006-6007-9. PMID 16715410. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  3. ^ "Entrez Gene: TRIB3 tribbles homolog 3 (Drosophila)".
  4. ^ a b c d e f g h Zhou, Ying (2008). "E3 ubiquitin ligase SIAH1 mediates ubiquitination and degradation of TRB3". Cell. Signal. 20 (5). England: 942–8. doi:10.1016/j.cellsig.2008.01.010. ISSN 0898-6568. PMID 18276110. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysummary=, and |laysource= (help); Unknown parameter |coauthors= ignored (|author= suggested) (help); Unknown parameter |month= ignored (help)
  5. ^ Wu, Min (2003). "SINK is a p65-interacting negative regulator of NF-kappaB-dependent transcription". J. Biol. Chem. 278 (29). United States: 27072–9. doi:10.1074/jbc.M209814200. ISSN 0021-9258. PMID 12736262. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysummary=, and |laysource= (help); Unknown parameter |coauthors= ignored (|author= suggested) (help); Unknown parameter |month= ignored (help)CS1 maint: unflagged free DOI (link)
  6. ^ Bowers, Alex J (2003). "SKIP3, a novel Drosophila tribbles ortholog, is overexpressed in human tumors and is regulated by hypoxia". Oncogene. 22 (18). England: 2823–35. doi:10.1038/sj.onc.1206367. ISSN 0950-9232. PMID 12743605. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysummary=, and |laysource= (help); Unknown parameter |coauthors= ignored (|author= suggested) (help); Unknown parameter |month= ignored (help)

Further reading

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