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Plasmodium RUF2 RNA: Difference between revisions

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'''RUF2''' is a [[non-coding RNA]](ncRNA) present within the [[plasmodium]] [[genome]]. [[bioinformatics|Bioinformatic]] studies predicted that RUF2 was present within the plasmodium genome and the expression of this ncRNA was verified by [[Northern Blot]]. <ref name=pmid17901154>{{Cite journal | first1 = K.
'''RUF2''' is a [[non-coding RNA]] (ncRNA) present within the [[plasmodium]] [[genome]]. [[bioinformatics|Bioinformatic]] studies predicted that RUF2 was present within the plasmodium genome and the expression of this ncRNA was verified by [[Northern Blot]]. <ref name=pmid17901154>{{Cite journal | first1 = K.
| last2 = Pearson | first2 = M.
| last2 = Pearson | first2 = M.
| last4 = Sterne-Weiler
| last4 = Sterne-Weiler

Revision as of 00:33, 31 August 2015

Plasmodium RNA of unknown function 2
Predicted secondary structure of RUF2
Identifiers
SymbolRUF2
RfamRF01579
Other data
RNA typesRNA
Domain(s)Plasmodium
PDB structuresPDBe

RUF2 is a non-coding RNA (ncRNA) present within the plasmodium genome. Bioinformatic studies predicted that RUF2 was present within the plasmodium genome and the expression of this ncRNA was verified by Northern Blot. [1] The location of this ncRNAs was subsequently mapped within the P. falciparum strain 3DF genome by primer extension. RUF2 is a novel RNA of unknown function but has shown to contain some structural similarity with the H/ACA box snoRNA but no known targets have been identified.

References

  1. ^ Chakrabarti, K.; Pearson, M.; Grate, L.; Sterne-Weiler, T.; Deans, J.; Donohue, P.; Ares Jr, R. (Nov 2007). "Structural RNAs of known and unknown function identified in malaria parasites by comparative genomics and RNA analysis" (Free full text). RNA. 13 (11): 1923–1939. doi:10.1261/rna.751807. ISSN 1355-8382. PMC 2040097. PMID 17901154.