Blast2GO

Blast2GO, first published in 2005^[1]^[2]^[3]^[4], is a bioinformatics software tool for the automatic, high-throughput functional annotation of novel sequence data (genes proteins). It makes use of the BLAST^[5] algorithm to identify similiar sequences to then transfers existing funcional annotation from yet characterised sequences to the novel one. The functional information is represented via the Gene Ontology (GO), a controlled vocabulary of functional attributes. The Gene Ontology, or GO, is a major bioinformatics initiative to unify the representation of gene and gene product attributes across all species.^[6]

References

^ Conesa, A (2005 Sep 15). "Blast2GO: a universal tool for annotation, visualization and analysis in functional genomics research". Bioinformatics (Oxford, England). 21 (18): 3674–6. doi:10.1093/bioinformatics/bti610. PMID 16081474. {{cite journal}}: Check date values in: |date= (help); Unknown parameter |coauthors= ignored (|author= suggested) (help); Unknown parameter |month= ignored (help)CS1 maint: date and year (link)
^ Götz, S (2008 Jun). "High-throughput functional annotation and data mining with the Blast2GO suite". Nucleic acids research. 36 (10): 3420–35. doi:10.1093/nar/gkn176. PMC 2425479. PMID 18445632. {{cite journal}}: Check date values in: |date= (help); Unknown parameter |coauthors= ignored (|author= suggested) (help)
^ Conesa, A (2008). "Blast2GO: A comprehensive suite for functional analysis in plant genomics". International journal of plant genomics. 2008: 619832. doi:10.1155/2008/619832. PMC 2375974. PMID 18483572. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)CS1 maint: unflagged free DOI (link)
^ Götz, S (2011 Apr 1). "B2G-FAR, a species-centered GO annotation repository". Bioinformatics (Oxford, England). 27 (7): 919–24. doi:10.1093/bioinformatics/btr059. PMC 3065692. PMID 21335611. {{cite journal}}: Check date values in: |date= (help); Unknown parameter |coauthors= ignored (|author= suggested) (help)
^ Altschul, SF (1990 Oct 5). "Basic local alignment search tool". Journal of molecular biology. 215 (3): 403–10. doi:10.1016/S0022-2836(05)80360-2. PMID 2231712. {{cite journal}}: Check date values in: |date= (help); Unknown parameter |coauthors= ignored (|author= suggested) (help)
^ The Gene Ontology Consortium (2008). "The Gene Ontology project in 2008". Nucleic Acids Res. 36 (Database issue): D440–4. doi:10.1093/nar/gkm883. PMC 2238979. PMID 17984083. {{cite journal}}: Unknown parameter |month= ignored (help)

External links

Official website Blast2GO - Tool for functional annotation of (novel) sequences and the analysis of annotation data.
Gene Ontology Tools — Provides access to the ontologies, software tools, annotated gene product lists, and reference documents describing the GO and its uses.

Category:Bioinformatics algorithms Category:Bioinformatics software Category:Laboratory software Category:Public domain software Category:Genomics Category:Omics

[b2g-1] Conesa, A (2005 Sep 15). "Blast2GO: a universal tool for annotation, visualization and analysis in functional genomics research". Bioinformatics (Oxford, England). 21 (18): 3674–6. doi:10.1093/bioinformatics/bti610. PMID 16081474. {{cite journal}}: Check date values in: |date= (help); Unknown parameter |coauthors= ignored (|author= suggested) (help); Unknown parameter |month= ignored (help)CS1 maint: date and year (link)

[2] Götz, S (2008 Jun). "High-throughput functional annotation and data mining with the Blast2GO suite". Nucleic acids research. 36 (10): 3420–35. doi:10.1093/nar/gkn176. PMC 2425479. PMID 18445632. {{cite journal}}: Check date values in: |date= (help); Unknown parameter |coauthors= ignored (|author= suggested) (help)

[3] Conesa, A (2008). "Blast2GO: A comprehensive suite for functional analysis in plant genomics". International journal of plant genomics. 2008: 619832. doi:10.1155/2008/619832. PMC 2375974. PMID 18483572. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)CS1 maint: unflagged free DOI (link)

[4] Götz, S (2011 Apr 1). "B2G-FAR, a species-centered GO annotation repository". Bioinformatics (Oxford, England). 27 (7): 919–24. doi:10.1093/bioinformatics/btr059. PMC 3065692. PMID 21335611. {{cite journal}}: Check date values in: |date= (help); Unknown parameter |coauthors= ignored (|author= suggested) (help)

[5] Altschul, SF (1990 Oct 5). "Basic local alignment search tool". Journal of molecular biology. 215 (3): 403–10. doi:10.1016/S0022-2836(05)80360-2. PMID 2231712. {{cite journal}}: Check date values in: |date= (help); Unknown parameter |coauthors= ignored (|author= suggested) (help)

[pmid17984083-6] The Gene Ontology Consortium (2008). "The Gene Ontology project in 2008". Nucleic Acids Res. 36 (Database issue): D440–4. doi:10.1093/nar/gkm883. PMC 2238979. PMID 17984083. {{cite journal}}: Unknown parameter |month= ignored (help)

[1]

[2]

[3]

[4]

[5]

[6]

v t e Genomics
Fields	Cognitive genomics Computational genomics Comparative genomics Functional genomics Genome project Human Genome Project Metagenomics Human Microbiome Project Pangenomics Personal genomics Population genomics Sociogenomics Structural genomics
Bioinformatics	Biochip Cheminformatics Chemogenomics Connectomics Human Connectome Project Epigenomics Human Epigenome Project Glycomics Immunomics Lipidomics Metabolomics Microbiomics Nutrigenomics Paleopolyploidy Pharmacogenetics Pharmacogenomics Systems biology Toxicogenomics Transcriptomics
Structural biology	Proteomics Human proteome project Call-map proteomics Structure-based drug design Expression proteomics
Research tools	2-D electrophoresis Mass spectrometer Electrospray ionization Matrix-assisted laser desorption ionization Matrix-assisted laser desorption ionization-time of flight mass spectrometer Microfluidic-based tools Isotope affinity tags Chromosome conformation capture
Organizations	DNA Data Bank of Japan (JP) European Molecular Biology Laboratory (EU) National Institutes of Health (USA) Wellcome Sanger Institute (UK)
List Category

See also

References

External links