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Carbuterol

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Carbuterol
Clinical data
ATC code
Legal status
Legal status
  • AU: S4 (Prescription only)
Identifiers
  • (RS)-{5-[2-(tert-butylamino)-1-hydroxyethyl]-2-hydroxyphenyl}urea
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.047.491 Edit this at Wikidata
Chemical and physical data
FormulaC13H21N3O3
Molar mass267.329 g·mol−1
3D model (JSmol)
ChiralityRacemic mixture
  • O=C(Nc1cc(ccc1O)C(O)CNC(C)(C)C)N
  • InChI=1S/C13H21N3O3/c1-13(2,3)15-7-11(18)8-4-5-10(17)9(6-8)16-12(14)19/h4-6,11,15,17-18H,7H2,1-3H3,(H3,14,16,19) checkY
  • Key:KEMXXQOFIRIICG-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Carbuterol (INN; carbuterol hydrochloride USAN) is a short-acting β2 adrenoreceptor agonist.[1][2]

Synthesis

[edit]
DE 2032642 

References

[edit]
  1. ^ Wardell JR, Colella DF, Shetzline A, Fowler PJ (April 1974). "Studies on carbuterol (SK & F 40383-A), a new selective bronchodilator agent". The Journal of Pharmacology and Experimental Therapeutics. 189 (1): 167–84. PMID 4823290.
  2. ^ DE 2032642, Lunts LH, Collin DT, "1-phenyl-2-aminäthanol-Derivate und Verfahren zu ihrer Herstellung un ihre Verwendung", published 1970, assigned to Allen & Hansburys Ltd