In this paper we are proposing a unified framework to demonstrate, how the alignment-free methods are instrumental in elucidating the evolutionary relationships ...

All of these methods treat the nucleotide or amino acid sequences as simple strings of character, and then consider occurrence frequencies and distribution of ...

In this paper we are proposing a unified framework to demonstrate, how the alignment-free methods are instrumental in elucidating the evolutionary relationships ...

Oct 3, 2017 · Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families.

Here, we present a community resource (http://afproject.org) to establish standards for comparing alignment-free approaches across different areas of sequence- ...

May 18, 2015 · This paper describes a completely alignment-free computational method, based on a blind unsupervised approach, to detect large-scale and small-scale genomic ...

Jul 1, 2007 · We investigate the use of a new score for alignment-free sequence comparison, called the score. It is based on comparing the frequencies of all fixed-length ...

Sep 5, 2022 · The output from an alignment-free sequence comparison is a similarity score, the interpretation of which is not straightforward.

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Alignment-free methods provide a computationally efficient alternative to alignment-based methods for large-scale sequence analysis. Several neural network- ...