May 12, 2009 · In the present work we develop a predictive QSAR model for the blockade of the hERG channel. Additionally, this specific end point is used ...
In the present work we develop a predictive QSAR model for the blockade of the hERG channel. Additionally, this specific end point is used as a test ...
Bias-correction of regression models: a case study on hERG inhibition ; Publication Type, Journal Article ; Year of Publication, 2009 ; Authors, Hansen, K, Rathke, ...
Bias-correction of regression models: a case study on hERG inhibition. K Hansen, F Rathke, T Schroeter, G Rast, T Fox, JM Kriegl, S Mika. Journal of chemical ...
... Bias\-Correction of Regression Models: A Case Study on hERG Inhibition", journal = "Journal of Chemical Information and Modelling", year = "2009", volume ...
Bias-correction of regression models: a case study on hERG inhibition. J Chem Inf Model. 2009; 49:1486–1496. [PubMed: 19435326]. 55. Nisius B, Göller AH ...
May 13, 2017 · The in-vitro and animal models were developed to screen for drug blockade to hERG leading to substantial increase in cost of drug development.
Bias-correction of regression models: a case study on hERG inhibition. June 01, 2009. [ MEDLINE Abstract ]. LQTA-QSAR: a new 4D-QSAR methodology. June 01 ...
Jul 1, 2013 · Logistic regression models using the MICE assay showed a significant reduction in false positives (Type 1 errors) and false negatives (Type 2 ...
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Sep 19, 2018 · We presented a pharmacoinformatics strategy using combined ligand and structure based models for the prediction of hERG inhibition potential (IC 50 ) of new ...