Discovering Subtype Specific n-Gram Motifs in Class C GPCR N-Termini. Authors. Caroline König, René Alquézar, Alfredo Vellido, Jesús Giraldo. Pages. 116 - 125.
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Jan 30, 2012 · In the present article, we aim to provide an overview of the exact sites and structural features involved in ligand recognition of the class C GPCRs.
Aug 31, 2024 · In this paper, we describe the use of feature selection techniques to build Support Vector Machine (SVM)-based classification models from ...
One major approach that has been utilized to enhance the plasma membrane expression of GPCRs in heterologous cells is the addition of sequences to the receptors ...
We show that this approach to classification is useful for finding class C. GPCR subtype-specific motifs. Keywords: G-Protein coupled receptors, pharmaco ...
Missing: Discovering Termini.
We report experiments that show that the extracellular N-terminal domain of the receptor suffices to retain the classification accuracy of the complete sequence ...
In this paper, we investigate the use of feature selection techniques to build Support Vector Machine (SVM)-based classification models from selected receptor ...
This review will cover recent advances in understanding the molecular mechanism underlying anterograde transport of the newly synthesized GPCRs.
Nov 10, 2021 · We present a GPCR superfamily-wide molecular mechanistic map of activation, and link determinants to ligand-binding, G-protein coupling, transduction and ...