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Our findings demonstrate that integrating both types of DNA methylation data with gene expression results in similar subtypes and outperforms existing methods.
Feb 27, 2024 · Our findings demonstrate that integrating both types of DNA methylation data with gene expression results in similar subtypes and outperforms ...
Investigating the Role of Gene Body Methylation and CpG ...
www.semanticscholar.org › paper › Inve...
Integrative analysis of DNA methylation and gene expression identified cervical cancer-specific diagnostic biomarkers · A DNA methylation‐based definition of ...
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DNA methylation is a complex epigenetic mechanism crucial to regulating gene expression in normal and tumor cells.
Nov 28, 2022 · Gene body methylation is widely involved in the expression regulation of many genes and is closely related to the occurrence and progression of malignant ...
Whole-genome CpG-resolution DNA Methylation Profiling of HNSCC ...
pmc.ncbi.nlm.nih.gov › PMC10467604
Aug 30, 2023 · Hypermethylation of promoter-associated CpG islands in cancer is well recognized as a mechanism to silence tumor suppressor genes (1).
Dec 13, 2019 · Several studies have reported that methylation markers are more sensitive than protein markers, and thus, cancer-specific methylation markers ...
Epigenetics, CpG methylation of CpG islands (CGI) and gene bodies (GBs), plays an important role in gene regulation and cancer biology, ...
In this review, we will discuss the molecular mechanisms of DNA methylation abnormalities in cancer as well as their therapeutic potential.
We explored DNA methylation-based signatures in association with breast cancer subtypes to assess their impact on clinical presentation and patient prognosis.
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