Apr 24, 2023 · Matrix-assisted laser desorption ionization mass spectrometry imaging (MALDI-MSI) has been successfully introduced to study AD pathology in brain tissue.
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Matrix-assisted laser desorption ionization mass spectrometry imaging (MALDI-MSI) has been successfully introduced to study AD pathology in brain tissue.
The NIA-AA research framework grouped biomarkers of Alzheimer's disease into those that detect amyloid β deposition [A], pathologic tau [T], and ...
In the present study, we aimed to evaluate how brain lipids are altered in Alzheimer's disease (AD)-like pathology by using mass spectrometry imaging (MSI).
Oct 16, 2017 · In recent years, MALDI-imaging mass spectrometry (IMS) has emerged as a powerful tool for investigating the distribution of proteins and small ...
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The aim of the present study was to find possible lipid regulations during the progression of AD in cortical areas that are affected by tau and amyloid ...
Mass spectrometry has emerged as a key technology to further our understanding of Alzheimer's disease pathology.
May 21, 2020 · Mass spectrometry imaging of free-floating brain sections detects pathological lipid distribution in a mouse model of Alzheimer's-like pathology ...
Jan 2, 2024 · Mass spectrometry imaging (MSI) can provide both molecular and spatial information within a tissue section in a label-free and nonspecific ...
Oct 31, 2024 · Changes in lipid compositions have been reported in AD using targeted mass spectrometry approaches and connected to neuroinflammation but ...