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Oct 31, 2020 · Here we develop a mechanistic mathematical model to predict the speed of progression to AIDS in individual untreated patients and patients ...
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A model of viral phenotypic mutations from R5 to X4 strains which reflect HIV late infection dynamics is presented and the action of Tumor Necrosis Factor ...
Mar 21, 2022 · To determine how the adaptive immune response impacts HIV evolution within a person, 24 different mathematical model variations were applied to ...
Sep 3, 2013 · Here we review developments in HIV modeling, emphasizing quantitative findings about HIV biology uncovered by studying acute infection, the response to drug ...
HIV infections are evolutionary processes on the time scale of a few years. The mathematical models are based on ordinary differential equations. Virus mutation ...
This article reviews mathematical models that outline the potential importance of this variability as a major factor for the develop- ment of AIDS. The ...
Aug 16, 2007 · During the HIV infection several quasispecies of the virus arise, which are able to use different coreceptors, in particular the CCR5 and ...
Our model for HIV infection includes two-strain and cell-to-cell transmission. · The dynamics of competition for two-strain and the viral permanence are studied.
Nov 28, 2005 · Abstract. We have modelled the within-patient evolutionary process during HIV infection. We have studied viral evolution at population.
The main factor which drives the progression to AIDS in this model is the asymmetry between the ability of viruses to infect cells and of the immune system to ...