Inhibitory networks have been shown to synchronize in the 20– 80 Hz range, and this activity correlates with some cognitive functions.
Experiments in cultured hippocampal cells show that the anesthetic propofol enhances inhibition through its action on the GABAA channel. Inhibitory networks ...
The most dramatic effect of propofol is the modulation of slow desensitization. This is only revealed when the network is driven at frequencies that are ...
The effect of anesthetic drugs at central synapses can be described quantitatively by developing kinetic models of ligand-gated ion channels.
Anesthetics significantly alter inhibitory signalling in the brain, and oscillatory activity in inhibitory networks in the CNS can play an important role in ...
Disruption of Coherent Oscillations in Inhibitory Networks With ... Modulation of coherent oscillations in inhibitory networks by anesthetics ...
Jul 19, 2023 · We report alpha-wave-amplitude and slow-wave-frequency modulatory processes that track continuously the transition between these states in humans anesthetized ...
Jun 24, 2003 · In short, the results suggest that an anesthetic, blocking Na and K channels state independently, can disrupt coherent oscillatory activity in ...
Frequency switches in inhibitory networks with anesthetics
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Our results suggest that the coherent frequency of inhibitory networks is very sensitive to desensitization. Thus, the effects of different anesthetics on ...
General anesthetics modulate functional connectivity and reduce brain network integration. We showed that such a process takes place even in young infants ...