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In this paper, the problem of the specific growth rate control in biological reactions in fed-batch mode is dealt with. It is assumed that only part of the ...
Only this limiting substrate will take palt in the equations. Many processes, in particular most pure cultures with one limiting substrate, can be described ...
This paper deals with the regulation of the biomass specific growth rate, which is an important goal in many fed-batch fermentation processes.
A stabilizing control law based on a partial state feedback with gain dependent on the output error feedback and gain saturation is proposed.
Oct 22, 2024 · Reliable control of the specific growth rate (μ) in fed-batch fermentations depends on the availability of accurate online estimations of ...
Nov 22, 2023 · In this study, an automatic control system is developed for the setpoint control of the cell biomass specific growth rate (SGR) in fed-batch cultivation ...
Jan 17, 2023 · To achieve better cell growth and high-yield recombinant protein, fed-batch culture is typically used for recombinant protein production in CHO cells.
Inferential control algorithms and systems for set-point control of the specific growth rate in fed-batch cultivation processes are presented.
Jul 23, 2020 · In a fed-batch, the feed rate is decisive to actively control the growth. In contrast, almost all repeated processes aim at substrate ...
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A new adaptive controller is designed for substrate control of a fed-batch bioreactor in the presence of input saturation and unknown varying control gain.