Microbial robustness denotes the ability of a microorganism to maintain a stable industrial performance (quantified as titers, rates, and yields) when facing one or multiple challenges (Figure 2B) [10].
Dec 10, 2021
In this work, we present a computational framework that searches for optimal and robust microbial strains that are able to produce target molecules.
In this work, we present a computational framework that searches for optimal and robust microbial strains that are able to produce target molecules.
People also ask
What are the methods of microbial strain improvement?
What is meant by microbial strains?
What are the criteria for selecting microbial strains for industrial fermentation?
What is the difference between a microbial species and a strain?
Our framework performs three tasks: it evaluates the parameter sensitivity of the microbial model, searches for the optimal genetic or fluxes design and finally ...
Metabolic engineering algorithms provide means to optimize a biological process leading to the improvement of a biotechnological interesting molecule.
Mar 1, 2024 · Robustness represents the ability of a strain to maintain a stable production performance (e.g. titer, yield, and productivity) when growth ...
Sep 24, 2018 · Systems and synthetic biology can be applied to design microbial strains that allow reliable and robust production on a large scale.
Dec 19, 2023 · Robustness quantification is a powerful tool for strain characterisation as it offers novel information on physiological and biochemical parameters.
Our framework performs three tasks: it evaluates the parameter sensitivity of the microbial model, searches for the optimal genetic or fluxes design and finally ...
Microbial robustness is a complex multifaceted concept that is important for the predictability and efficiency of biological production. Robustness refers to ...