@phdthesis{dissertation, author = {Paetzold, Johannes Christian}, title = {Whole Brain Vasculature Analysis Using Advanced Learning Models}, year = {2023}, school = {Technische Universität München}, pages = {166}, language = {en}, abstract = {The brain's vascular network supplies oxygen to the brain's 86 billion neurons, firmly linking the microvasculature to the neural organization. This thesis reports my work on developing machine learning models to understand brain vessels. At the core of my work are three studies: 1) The first study shows the first deep-learning-based segmentation of the entire brain vasculature. 2) We formulate a novel, topology-preserving loss function with theoretical proofs up to homotopy equivalence. 3) We convert the segmentations to a graph representation and benchmark a diverse set of graph convolutional networks on link prediction and node classification. }, keywords = {}, note = {}, url = {https://mediatum.ub.tum.de/1659236}, }