TY - JOUR ID - city4703 UR - https://openaccess.city.ac.uk/id/eprint/4703/ IS - 11 A1 - Yang, X. A1 - Slabaugh, G. G. N2 - Purpose: The rectal tube (RT) is a common source of false positives (FPs) in computer-aided detection (CAD) systems for CT colonography. A robust and efficient detection of RT can improve CAD performance by eliminating such ?obvious? FPs and increase radiologists? confidence in CAD. Methods: In this paper, we present a novel and robust bottom-up approach to detect the RT. Probabilistic models, trained using kernel density estimation on simple low-level features, are employed to rank and select the most likely RT tube candidate on each axial slice. Then, a shape model, robustly estimated using Random Sample Consensus (RANSAC), infers the global RT path from the selected local detections. Subimages around the RT path are projected into a subspace formed from training subimages of the RT. A quadratic discriminant analysis (QDA) provides a classification of a subimage as RT or non-RT based on the projection. Finally, a bottom-top clustering method is proposed to merge the classification predictions together to locate the tip position of the RT. Results: Our method is validated using a diverse database, including data from five hospitals. On a testing data with 21 patients (42 volumes), 99.5% of annotated RT paths have been successfully detected. Evaluated with CAD, 98.4% of FPs caused by the RT have been detected and removed without any loss of sensitivity. Conclusion: The proposed method demonstrates a high detection rate of the RT path, and when tested in a CAD system, reduces FPs caused by the RT without the loss of sensitivity. VL - 38 TI - A robust and efficient approach to detect 3D rectal tubes from CT colonography AV - public EP - 6247 Y1 - 2011/10/27/ PB - Wiley JF - Medical Physics KW - Rectal Tube KW - RANSAC KW - CAD KW - eigenspace KW - CT colonography SN - 0094-2405 SP - 6238 ER -