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Molecular & Computational biology news
Healthy gut bacteria that feed on sugar analyzed for the first time
A microbe that is associated with good health and found in the lower part of the gut has been comprehensively analyzed and found to have a focused diet breaking down sugars locked away in mucus.
Cell & Microbiology
3 hours ago
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Specific neurons may explain why maggots love the texture of decaying fruit
A study led by Nikita Komarov and Simon Sprecher at the University of Fribourg, Switzerland, has discovered neurons in the fly larva mouth that allow the taste of food texture.
Plants & Animals
18 hours ago
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Bats' genetic adaptations: How they tolerate coronaviruses without becoming ill
New research from the University of St Andrews has shown that bats can tolerate coronaviruses and other viruses without becoming ill, thanks to special adaptations of their immune system.
Evolution
21 hours ago
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58
Bioengineering advance allows scientists to accurately predict and engineer protein metalation
Researchers at Durham University have achieved a major advancement in understanding how proteins bind metals inside cells, a process crucial to life. The study, published in Nature Communications, introduces a pioneering ...
Biotechnology
21 hours ago
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Future antibiotics face early bacterial resistance challenges, studies show
Researchers from the HUN-REN Biological Research Centre, Szeged (Hungary), have made a concerning discovery about the future of antibiotics. Two recent studies, published just days apart in Nature Microbiology and Science ...
Cell & Microbiology
21 hours ago
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AI-driven multi-modal framework improves protein editing for science and medicine
Researchers from Zhejiang University and HKUST (Guangzhou) have developed a cutting-edge AI model, ProtET, that leverages multi-modal learning to enable controllable protein editing through text-based instructions. This innovative ...
Biotechnology
Jan 29, 2025
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After inversion by CRISPR/Cas, the epigenetic state of plant chromosomes remains stable
The epigenetic state of chromatin, gene activity, and chromosomal positions are interrelated. A research team from the IPK Leibniz Institute (IPK) and the Karlsruhe Institute of Technology (KIT) has investigated how the chromosomal ...
Plants & Animals
Jan 29, 2025
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62
AI model learns generalized 'language' of regulatory genomics, predicts cellular stories
A team of investigators from Dana-Farber Cancer Institute, The Broad Institute of MIT and Harvard, Google, and Columbia University have created an artificial intelligence model that can predict which genes are expressed in ...
Cell & Microbiology
Jan 29, 2025
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25
High-speed microscopy technique reveals dynamic E. coli membrane stiffness
Light and electron microscopy have distinct limitations. Light microscopy makes it difficult to resolve smaller and smaller features, and electron microscopy resolves small structures, but samples must be meticulously prepared, ...
Cell & Microbiology
Jan 29, 2025
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Crucial plant protein traced back to over 600 millions years ago, predating the first plant
Wageningen researchers have discovered that a vital plant protein originated more than 600 million years ago, long before the first plants existed. They traced its origins back to an evolutionary event in a distant unicellular ...
Evolution
Jan 29, 2025
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1
Scientists discover a genetic lifeline for the endangered shortfin mako shark
Shortfin makos are the fastest sharks in the sea, but they're failing to outpace the scale of overfishing that is driving them to extinction. Global demand for their meat and lucrative fins has placed this predator on the ...
Plants & Animals
Jan 29, 2025
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37
AI-based platform designs peptides to target 'undruggable' proteins
Biomedical engineers at Duke University have developed an AI-based platform that designs short proteins, termed peptides, capable of binding and destroying previously undruggable disease-causing proteins. Inspired by OpenAI's ...
Biotechnology
Jan 29, 2025
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Human genetics provides clues to why DNA regulatory regions get 'loopy'
DNA transcription is the vital first step needed for switching on our genes. For a gene to be switched on, it must be acted upon by an enzyme called RNA polymerase. This is a molecular machine which can read DNA and create ...
Molecular & Computational biology
Jan 29, 2025
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64
How microbes help detoxify the atmosphere: Study provides atomic-level insights
Melbourne researchers have discovered crucial new information about how microbes consume huge amounts of carbon monoxide (CO) and help reduce levels of this deadly gas.
Cell & Microbiology
Jan 29, 2025
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30
Researchers illuminate new structures of a critical amyloid protein
The tiny protein known as transthyretin can cause big problems in the body when it misfolds after secretion. While healthy transthyretin moves hormones through blood and spinal fluid, misfolded versions of the protein form ...
Molecular & Computational biology
Jan 29, 2025
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30
Mapping of a gigantic salamander genome reveals secrets of regeneration
Researchers at Karolinska Institutet, in collaboration with teams from Lund University and the Center for Regenerative Therapies Dresden (CRTD), have mapped the genome of the Iberian ribbed newt and revealed how the composition ...
Plants & Animals
Jan 29, 2025
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62
Hijacking the ribosome: New insights into how poxviruses boost protein production
Northwestern Medicine scientists have uncovered new details explaining how poxviruses manipulate host cells to enhance their own protein production, according to a study published in Cell Reports.
Cell & Microbiology
Jan 28, 2025
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Genetic 'fingerprint' in bacteria can predict drug resistance
Antibiotic resistance is a global public health crisis responsible for more than a million deaths annually. By 2050, the World Health Organization estimates it could surpass cancer and heart disease as the leading cause of ...
Cell & Microbiology
Jan 28, 2025
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70
How a multitasking protein keeps the body's clock in sync
If your genes could set an alarm clock, EZH1 might be the one ringing the bell. A new study has revealed how this underappreciated protein ensures the rhythmic expression of genes in skeletal muscle, aligning them with the ...
Molecular & Computational biology
Jan 28, 2025
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New numbering system standardizes protein domain comparison for better research
Adhesion G protein-coupled receptors (GPCRs) are a group of cell-surface sensors associated with many body functions and diseases. However, they are not yet sufficiently understood to be exploited for therapies.
Molecular & Computational biology
Jan 28, 2025
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