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Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients.
Sokol H, Pigneur B, Watterlot L, Lakhdari O, Bermúdez-Humarán LG, Gratadoux JJ, Blugeon S, Bridonneau C, Furet JP, Corthier G, Grangette C, Vasquez N, Pochart P, Trugnan G, Thomas G, Blottière HM, Doré J, Marteau P, Seksik P, Langella P. Sokol H, et al. Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16731-6. doi: 10.1073/pnas.0804812105. Epub 2008 Oct 20. Proc Natl Acad Sci U S A. 2008. PMID: 18936492 Free PMC article. Clinical Trial.
Production of human papillomavirus type 16 E7 protein in Lactococcus lactis.
Bermúdez-Humarán LG, Langella P, Miyoshi A, Gruss A, Guerra RT, Montes de Oca-Luna R, Le Loir Y. Bermúdez-Humarán LG, et al. Appl Environ Microbiol. 2002 Feb;68(2):917-22. doi: 10.1128/AEM.68.2.917-922.2002. Appl Environ Microbiol. 2002. PMID: 11823236 Free PMC article.
Controlled production of stable heterologous proteins in Lactococcus lactis.
Miyoshi A, Poquet I, Azevedo V, Commissaire J, Bermudez-Humaran L, Domakova E, Le Loir Y, Oliveira SC, Gruss A, Langella P. Miyoshi A, et al. Appl Environ Microbiol. 2002 Jun;68(6):3141-6. doi: 10.1128/AEM.68.6.3141-3146.2002. Appl Environ Microbiol. 2002. PMID: 12039780 Free PMC article.
A novel mucosal vaccine based on live Lactococci expressing E7 antigen and IL-12 induces systemic and mucosal immune responses and protects mice against human papillomavirus type 16-induced tumors.
Bermúdez-Humarán LG, Cortes-Perez NG, Lefèvre F, Guimarães V, Rabot S, Alcocer-Gonzalez JM, Gratadoux JJ, Rodriguez-Padilla C, Tamez-Guerra RS, Corthier G, Gruss A, Langella P. Bermúdez-Humarán LG, et al. J Immunol. 2005 Dec 1;175(11):7297-302. doi: 10.4049/jimmunol.175.11.7297. J Immunol. 2005. PMID: 16301635
151 results