| SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids J Jansen, KC Reimer, JS Nagai, FS Varghese, GJ Overheul, M de Beer, ... Cell stem cell 29 (2), 217-231. e8, 2022 | 199 | 2022 |
| Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors ML Boby, D Fearon, M Ferla, M Filep, L Koekemoer, MC Robinson, ... Science 382 (6671), eabo7201, 2023 | 145* | 2023 |
| Crystal structure of Zika virus NS5 RNA-dependent RNA polymerase AS Godoy, GMA Lima, KIZ Oliveira, NU Torres, FV Maluf, RVC Guido, ... Nature communications 8 (1), 14764, 2017 | 125 | 2017 |
| Molecular mechanism of peroxisome proliferator-activated receptor α activation by WY14643: a new mode of ligand recognition and receptor stabilization A Bernardes, PCT Souza, JRC Muniz, CG Ricci, SD Ayers, NM Parekh, ... Journal of molecular biology 425 (16), 2878-2893, 2013 | 114 | 2013 |
| Structural basis of nirmatrelvir and ensitrelvir activity against naturally occurring polymorphisms of the SARS-CoV-2 main protease GD Noske, E de Souza Silva, MO de Godoy, I Dolci, RS Fernandes, ... Journal of Biological Chemistry 299 (3), 2023 | 69 | 2023 |
| A Crystallographic Snapshot of SARS-CoV-2 Main Protease Maturation Process G Noske, A Nakamura, V Gawriljuk, R Fernandes, G Lima, H Rosa, ... Journal of Molecular Biology 433 (18), 167118, 2021 | 60 | 2021 |
| Machine learning models identify inhibitors of SARS-CoV-2 VO Gawriljuk, PPK Zin, AC Puhl, KM Zorn, DH Foil, TR Lane, B Hurst, ... Journal of chemical information and modeling 61 (9), 4224-4235, 2021 | 49 | 2021 |
| An atomic model for the human septin hexamer by cryo-EM DC Mendonça, SL Guimarães, HDM Pereira, AA Pinto, MA de Farias, ... Journal of molecular biology 433 (15), 167096, 2021 | 40 | 2021 |
| Discovery of SARS-CoV-2 main protease inhibitors using a synthesis-directed de novo design model A Morris, W McCorkindale, N Drayman, JD Chodera, S Tay, N London, ... Chemical Communications 57 (48), 5909-5912, 2021 | 37 | 2021 |
| Reporter replicons for antiviral drug discovery against positive single-stranded RNA viruses RS Fernandes, MCLC Freire, RV Bueno, AS Godoy, LHVG Gil, G Oliva Viruses 12 (6), 598, 2020 | 34 | 2020 |
| Recombinant Trichoderma harzianum endoglucanase I (Cel7B) is a highly acidic and promiscuous carbohydrate-active enzyme VOA Pellegrini, VI Serpa, AS Godoy, CM Camilo, A Bernardes, ... Applied microbiology and biotechnology 99, 9591-9604, 2015 | 33 | 2015 |
| Crystal structure of β1→6‐galactosidase from Bifidobacterium bifidum S17: trimeric architecture, molecular determinants of the enzymatic activity and its inhibition … AS Godoy, CM Camilo, MA Kadowaki, HS Muniz, M Espirito Santo, ... The FEBS Journal 283 (22), 4097-4112, 2016 | 31 | 2016 |
| Non-toxic dimeric peptides derived from the bothropstoxin-I are potent SARS-CoV-2 and papain-like protease inhibitors MCLC Freire, GD Noske, NV Bitencourt, PRS Sanches, NA Santos-Filho, ... Molecules 26 (16), 4896, 2021 | 30 | 2021 |
| Development of machine learning models and the discovery of a new antiviral compound against yellow fever virus VO Gawriljuk, DH Foil, AC Puhl, KM Zorn, TR Lane, O Riabova, ... Journal of chemical information and modeling 61 (8), 3804-3813, 2021 | 24 | 2021 |
| Discovery of an imidazonaphthyridine and a riminophenazine as potent anti-Zika virus agents through a replicon-based high-throughput screening RS Fernandes, AS de Godoy, IA Santos, GD Noske, KIZ de Oliveira, ... Virus Research 299, 198388, 2021 | 23 | 2021 |
| Structural characterization and polymorphism analysis of the NS2B-NS3 protease from the 2017 Brazilian circulating strain of Yellow Fever virus GD Noske, VO Gawriljuk, RS Fernandes, ND Furtado, MC Bonaldo, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1864 (4), 129521, 2020 | 21 | 2020 |
| Pyronaridine protects against SARS-CoV-2 infection in mouse AC Puhl, GF Gomes, S Damasceno, AS Godoy, GD Noske, AM Nakamura, ... ACS Infectious Diseases 8 (6), 1147-1160, 2022 | 20 | 2022 |
| Structure, computational and biochemical analysis of PcCel45A endoglucanase from Phanerochaete chrysosporium and catalytic mechanisms of GH45 subfamily C members AS Godoy, CS Pereira, MP Ramia, RL Silveira, CM Camilo, MA Kadowaki, ... Scientific reports 8 (1), 1-14, 2018 | 18 | 2018 |
| Enzymatic versatility and thermostability of a new aryl-alcohol oxidase from Thermothelomyces thermophilus M77 MAS Kadowaki, PMR Higasi, MO de Godoy, EA de Araujo, AS Godoy, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1864 (10), 129681, 2020 | 16 | 2020 |
| Discovery and characterization of peptide inhibitors for calcium and integrin binding protein 1 AC Puhl, JW Bogart, VA Haberman, JE Larson, AS Godoy, ... ACS chemical biology 15 (6), 1505-1516, 2020 | 16 | 2020 |
Igor PolikarpovProfessor TitularVerified email at ifsc.usp.br
