AI on a chip
Artificial intelligence (AI) has dramatically changed the landscape of science, industry,
defence, and medicine in the last several years. Supported by considerably enhanced …
defence, and medicine in the last several years. Supported by considerably enhanced …
Perspectives on liquid biopsy for label‐free detection of “circulating tumor cells” through intelligent lab‐on‐chips
Circulating tumor cells (CTCs) are rare tumor cells released from primary, metastatic, or
recurrent tumors in the peripheral blood of cancer patients. CTCs isolation from peripheral …
recurrent tumors in the peripheral blood of cancer patients. CTCs isolation from peripheral …
Multispectral quantitative phase imaging using a diffractive optical network
As a label‐free imaging technique, quantitative phase imaging (QPI) provides optical path
length information of transparent specimens for various applications in biology, materials …
length information of transparent specimens for various applications in biology, materials …
PARC: ultrafast and accurate clustering of phenotypic data of millions of single cells
Motivation New single-cell technologies continue to fuel the explosive growth in the scale of
heterogeneous single-cell data. However, existing computational methods are inadequately …
heterogeneous single-cell data. However, existing computational methods are inadequately …
Cell morphology-based machine learning models for human cell state classification
Y Li, CM Nowak, U Pham, K Nguyen… - NPJ systems biology and …, 2021 - nature.com
Herein, we implement and access machine learning architectures to ascertain models that
differentiate healthy from apoptotic cells using exclusively forward (FSC) and side (SSC) …
differentiate healthy from apoptotic cells using exclusively forward (FSC) and side (SSC) …
Deep-learning-assisted biophysical imaging cytometry at massive throughput delineates cell population heterogeneity
The association of the intrinsic optical and biophysical properties of cells to homeostasis and
pathogenesis has long been acknowledged. Defining these label-free cellular features …
pathogenesis has long been acknowledged. Defining these label-free cellular features …
Quantitative phase imaging flow cytometry for ultra‐large‐scale single‐cell biophysical phenotyping
Cellular biophysical properties are the effective label‐free phenotypes indicative of
differences in cell types, states, and functions. However, current biophysical phenotyping …
differences in cell types, states, and functions. However, current biophysical phenotyping …
Optofluidic imaging meets deep learning: from merging to emerging
Propelled by the striking advances in optical microscopy and deep learning (DL), the role of
imaging in lab-on-a-chip has dramatically been transformed from a silo inspection tool to a …
imaging in lab-on-a-chip has dramatically been transformed from a silo inspection tool to a …
Quantitative scoring of epithelial and mesenchymal qualities of cancer cells using machine learning and quantitative phase imaging
Significance: We introduce an application of machine learning trained on optical phase
features of epithelial and mesenchymal cells to grade cancer cells' morphologies, relevant to …
features of epithelial and mesenchymal cells to grade cancer cells' morphologies, relevant to …
Finding intracellular lipid droplets from the single-cell biolens' signature in a holographic flow-cytometry assay
In recent years, intracellular LDs have been discovered to play an important role in several
pathologies. Therefore, detection of LDs would provide an in-demand diagnostic tool if …
pathologies. Therefore, detection of LDs would provide an in-demand diagnostic tool if …