Objective: To provide recommendations to patients, physicians, and other health care
providers on several issues involving deep brain stimulation (DBS) for Parkinson disease …

High-frequency deep brain stimulation (DBS) of the thalamus or basal ganglia represents an
effective clinical technique for the treatment of several medically refractory movement …

Solidification behaviour controls the size and shape of grains, the microstructure, the extent
of segregation, the distribution of inclusions, the extent of defects such as porosity and hot …

Background—Carotid stenting is a less invasive percutaneous procedure than carotid
endarterectomy for the treatment of carotid stenosis. Reports suggest that it can be …

To clarify the mechanism underlying improvement of parkinsonian signs by high-frequency
electrical stimulation (HFS) of the subthalamic nucleus (STN), we investigated the effects of …

Background In an open-label phase 1 trial, gene delivery of the trophic factor neurturin via
an adeno-associated type-2 vector (AAV2) was well tolerated and seemed to improve motor …

Background Surgical endarterectomy has been shown to be superior to medical
management in the management of severe carotid stenosis in both symptomatic and …

The effects of posterior internal pallidal ablation (GPi pallidotomy) on parkinsonian signs
and symptoms were studied in 15 patients with medically intracally intractable Parkinson's …

Microelectrode recording was performed in the basal ganglia of 3 patients with generalized
dystonia and 1 patient with hemiballismus secondary to a brainstem hemorrhage. Neuronal …

Objective: The goal of this project was to develop a quantitative understanding of the volume
of axonal tissue directly activated by deep brain stimulation (DBS) of the subthalamic …