… , PKC’s continued success is evident from both the number and the quality of submissions.
PKC 2009 re… Based on extensive discussions, the PKC 2009 best paper award was given to …

… In summary, these results demonstrated the IR-dependent activation of cytoplasmic PKC
signaling and discovered the consecutive PKC-dependent activation of prosurvival signaling …

… To facilitate comparisons of current activity with simultaneous FRET measurements of PKC
activity, we chose to portray increases in PKC phosphorylation as a decrease in the ratio of …

… drugs indicated that distinct PKC isoforms are required for … PKC isoforms may serve as
drug targets for different T cell mediated adaptive immune responses (Baier and Wagner, 2009…

… We also show that re-activation of MAPK signalling has a dominant role in regulating PKC …
sensitivity to PKC inhibitor monotherapy. Thus, combination therapies targeting PKC and PKC-…

… The most potent compound was phorbol 12-myristate 13-acetate (PMA, also referred to as
TPA for 12–0-… Citation2009). With better patient survival generally associated with higher …

… (a “Ca 2+ wave”); the role that diacylglycerol-activated PKC might play in the … 12-O-tetradecanoylphorbol
13-acetate- or 1,2-dioctanyl-sn-glycerol-induced activation of PKC slows the Ca …

… activating PKC using a phorbol ester. Finally, we tested whether PKC-α, a calcium-dependent
PKC … 12). Recently, we showed that vasopressin-stimulated urea permeability was further …

… Src inhibitors PD173955, PD180970, and SU6656, and PKC inhibitors bisindolylmaleimide
and 12-O-tetradecanoylphorbol 13-acetate (TPA) were purchased from Calbiochem. Cells …

… Reconstitution of PKCδ in patient-derived EBV-transformed B-cell lines partially restored
phorbol-12-myristate-13-acetate–induced cell death. In summary, homozygous PRKCD …