The chemical selectivity and the sensor replacements challenge the applications of electronic noses (E-noses) in the detection of complex odors in natural environments. A hybrid of virtual sensor array (VSA) and multisensor array (MSA) was proposed in this article to enhance the selectivity of an E-nose by operating one of the sensor units at multiparameters instead of adding more sensors conventionally. The hybrid sensor array was developed based on four wireless electrodeless quartz crystal microbalances with dissipation (WE-QCM-D), in which the sensor units could be replaced conveniently. Each WE-QCM-D was worked at a different fundamental frequency (6, 7.45, 8, and 9 MHz) and coated with a different sensing film. The VSA was created on the WE-QCM-D working at 6 MHz, and the dynamic viscoelasticity of the sensing film was probed by tracking the resonant frequency shifts and acoustic energy dissipation at multiple harmonics. In practice, the recognition accuracy of the hybrid system on the volatile organic compounds (VOCs) in the headspaces of seven Chinese herbs was improved by 3%–6% as VSA helped the discrimination between structurally similar VOCs. The results indicate that the VOC selectivity of an E-nose could be improved by working in a VSA mode without increasing the complexity of its geometry. The hybrid of MSA and VSA would be a promising alternative strategy to promote the realization of a low cost and compact artificial olfactory system with high performance and stability.