Accelerating FaST-LMM for epistasis tests

H Martínez, S Barrachina, M Castillo… - … and Architectures for …, 2017 - Springer
Algorithms and Architectures for Parallel Processing: 17th International …, 2017Springer
We introduce an enhanced version of FaST-LMM that maintains the sensitivity of this
software when applied to identify epistasis interactions while delivering an acceleration
factor that is close to 7.5 * on a server equipped with a state-of-the-art graphics coprocessor.
This performance boost is obtained from the combined effects of integrating a dictionary for
faster storage of the test results; a re-organization of the original FaST-LMM Python code;
and off-loading of compute-intensive parts to the graphics accelerator.
Abstract
We introduce an enhanced version of FaST-LMM that maintains the sensitivity of this software when applied to identify epistasis interactions while delivering an acceleration factor that is close to 7.5 on a server equipped with a state-of-the-art graphics coprocessor. This performance boost is obtained from the combined effects of integrating a dictionary for faster storage of the test results; a re-organization of the original FaST-LMM Python code; and off-loading of compute-intensive parts to the graphics accelerator.
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