User profiles for Alex S. Felmeister
 | Alex S. FelmeisterIllumina, Inc. Verified email at illumina.com Cited by 638 |
[HTML][HTML] A longitudinal footprint of genetic epilepsies using automated electronic medical record interpretation
…, M O'Brien, AK Gonzalez, AS Felmeister… - Genetics in …, 2020 - Elsevier
Purpose Childhood epilepsies have a strong genetic contribution, but the disease trajectory
for many genetic etiologies remains unknown. Electronic medical record (EMR) data …
for many genetic etiologies remains unknown. Electronic medical record (EMR) data …
Phenotypic homogeneity in childhood epilepsies evolves in gene-specific patterns across 3251 patient-years of clinical data
…, MC Kaufman, AK Gonzalez, AS Felmeister… - European Journal of …, 2021 - nature.com
While genetic studies of epilepsies can be performed in thousands of individuals, phenotyping
remains a manual, non-scalable task. A particular challenge is capturing the evolution of …
remains a manual, non-scalable task. A particular challenge is capturing the evolution of …
The biorepository portal toolkit: an honest brokered, modular service oriented software tool set for biospecimen-driven translational research
Background High throughput molecular sequencing and increased biospecimen variety have
introduced significant informatics challenges for research biorepository infrastructures. We …
introduced significant informatics challenges for research biorepository infrastructures. We …
A Framework for Analysis, Ontological Evaluation, and Visualization in Preparation to Predictive Analytics in Pediatric Brain Tumor Research
AS Felmeister, AJ Waanders, JL Mason… - 2020 IEEE …, 2020 - ieeexplore.ieee.org
We provide a generalizable framework for the systematic analysis of complicated, longitudinal
clinical features in pediatric cancer. We use a threefold pipeline of exploratory data …
clinical features in pediatric cancer. We use a threefold pipeline of exploratory data …
[PDF][PDF] A Unified Framework for Collecting, Annotating, Modeling and Prediction from Phenotypes in Multi-Institutional Pediatric Data Resources
AS Felmeister - 2019 - researchdiscovery.drexel.edu
Predictive models on sequential observational clinical data have helped make headway
utilizing large sets of this data collected from health systems from electronic medical record (…
utilizing large sets of this data collected from health systems from electronic medical record (…
Preliminary exploratory data analysis of simulated national clinical data research network for future use in annotation of a rare tumor biobanking initiative
AS Felmeister, AJ Waanders, SES Leary… - 2017 IEEE …, 2017 - ieeexplore.ieee.org
Observational data resources based on the capture of clinical data in the electronic health
record (EHR) have produced significant learning opportunities in many areas of medicine. …
record (EHR) have produced significant learning opportunities in many areas of medicine. …
Scalable biobanking: a modular electronic honest broker and biorepository for integrated clinical, specimen and genomic research
AS Felmeister, TJ Rivera, AJ Masino… - 2015 IEEE …, 2015 - ieeexplore.ieee.org
Biorepository research has introduced significant challenges to biomedical informatics
systems design and implementation. We take a best-of-breed system integrative approach to …
systems design and implementation. We take a best-of-breed system integrative approach to …
gene-15. Cavatica-a pediatric genomic cloud empowering data discovery through the pediatric brain tumor atlas
INTRODUCTION: The 2016 revision of the WHO classification of CNS tumors defines
molecular subtypes and diagnosis in addition to histopathology. However, there is not an …
molecular subtypes and diagnosis in addition to histopathology. However, there is not an …
Abstract LB-008: The Pediatric Brain Tumor Atlas: building an integrated, multi-platform data-rich ecosystem for collaborative discovery in the cloud
Pediatric brain tumors are the leading cause of disease-related death in children. However,
despite large scale data-driven efforts for pediatric cancers by the NIH (eg TARGET, …
despite large scale data-driven efforts for pediatric cancers by the NIH (eg TARGET, …
Accelerating pediatric brain tumor research through team science solutions
A Christini, AJ Waanders, JB Wagenaar, AS Felmeister… - Cancer Research, 2017 - AACR
Introduction: The Children’s Brain Tumor Tissue Consortium (CBTTC), an international
repository of genomic and phenotypic data, has partnered with Blackfynn, Inc., to create a cloud-…
repository of genomic and phenotypic data, has partnered with Blackfynn, Inc., to create a cloud-…