Computing in biological time: the design of an anticocaine molecule
PF Gorder - Computing in Science & Engineering, 2006 - ieeexplore.ieee.org
PF Gorder
Computing in Science & Engineering, 2006•ieeexplore.ieee.orgWe measure our lives in years, plan our activities according to orcadian rhythms, and gauge
our health by counting breaths and heartbeats. Yet, our bodies' most natural timescale is
only a fraction of a second. The cellular processes that keep us alive occur so fast that
scientists often can't directly observe them, but computer simulations fill that gap amazingly
well-considering that a single biochemical reaction that lasts only a billionth of a second
might require an entire day to simulate on a supercomputer. At the molecular level, life …
our health by counting breaths and heartbeats. Yet, our bodies' most natural timescale is
only a fraction of a second. The cellular processes that keep us alive occur so fast that
scientists often can't directly observe them, but computer simulations fill that gap amazingly
well-considering that a single biochemical reaction that lasts only a billionth of a second
might require an entire day to simulate on a supercomputer. At the molecular level, life …
We measure our lives in years, plan our activities according to orcadian rhythms, and gauge our health by counting breaths and heartbeats. Yet, our bodies' most natural timescale is only a fraction of a second. The cellular processes that keep us alive occur so fast that scientists often can't directly observe them, but computer simulations fill that gap amazingly well-considering that a single biochemical reaction that lasts only a billionth of a second might require an entire day to simulate on a supercomputer. At the molecular level, life already moves fast. In search of a better anticocaine medication, scientists at the University of Kentucky used computer simulations to create a "souped-up" version of the human enzyme that breaks down the drug even faster.
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