Long non-coding RNAs in prostate cancer: Functional roles and clinical implications

YH Xu, JL Deng, G Wang, YS Zhu - Cancer letters, 2019 - Elsevier
… Author links open overlay panel Yun-Hua Xu a b c d 1 , Jun-Li Deng a b c d 1 , Guo Wang
a … Li Y. found that SChLAP1 negatively regulated miR-198 and subsequently affected the …

Emerging role of long non-coding RNAs in cisplatin resistance

Y Hu, QN Zhu, JL Deng, ZX Li, G Wang… - OncoTargets and …, 2018 - Taylor & Francis
Cisplatin (CDDP) is one of the most commonly used chemotherapy drugs for the treatment
of various cancers. Although platinum-based therapies are highly efficacious against rapidly …

Insights into the involvement of long non-coding RNAs in doxorubicin resistance of cancer

HB Zhang, Y Hu, JL Deng, GY Fang… - Frontiers in …, 2023 - frontiersin.org
Doxorubicin is one of the most classical chemotherapeutic drugs for the treatment of cancer.
However, resistance to the cytotoxic effects of doxorubicin in tumor cells remains a major …

Identification of potential crucial genes and key pathways in breast cancer using bioinformatic analysis

JL Deng, Y Xu, G Wang - Frontiers in genetics, 2019 - frontiersin.org
Background: The molecular mechanism of tumorigenesis remains to be fully understood in
breast cancer. It is urgently required to identify genes that are associated with breast cancer …

A combined optimization prediction model for earth-rock dam seepage pressure using multi-machine learning fusion with decomposition data-driven

B Liu, W Cen, C Zheng, D Li, L Wang - Expert Systems with Applications, 2024 - Elsevier
Seepage pressure data analysis is considered one of the most direct ways to evaluate
seepage safety in dam engineering. Therefore, accurate and consistent prediction of seepage …

[HTML][HTML] LncRNA H19 is a major mediator of doxorubicin chemoresistance in breast cancer cells through a cullin4A-MDR1 pathway

…, G Wang, Y Guo, Y Peng, R Zhang, JL Deng, ZX Li… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Abstract Development of chemoresistance is a persistent problem during cancer treatment.
Long non-coding RNAs (LncRNAs) are currently emerging as an integral functional …

Identification of candidate genes associated with breast cancer prognosis

YH Xu, JL Deng, LP Wang, HB Zhang, L Tang… - DNA and cell …, 2020 - liebertpub.com
Breast cancer (BC) is the most malignant tumor in women. The molecular mechanisms
underlying tumorigenesis still need to be further elucidated. It is necessary to investigate novel …

Statins induce cell apoptosis through a modulation of AKT/FOXO1 pathway in prostate cancer cells

JL Deng, R Zhang, Y Zeng, YS Zhu… - Cancer Management and …, 2019 - Taylor & Francis
Background: In recent years, statins have been frequently investigated in neoplasms.
However, the potential roles of statins on prostate cancer cells and the underlying mechanisms …

Impact of transient seepage on slope stability of earth-rock dams with geomembrane barrier defects

W Cen, D Li, H Wang - Environmental Geotechnics, 2019 - icevirtuallibrary.com
The water–air two-phase unsaturated seepage theory was employed to analyse the transient
seepage field of an earth-rock dam with an impervious geomembrane barrier during rapid …

Laboratory Testing and Numerical Modeling of Creep Behavior of HDPE Geomembranes under Multistage Loading

D Li, W Cen, X Ren, Z Wen - Geotechnical …, 2024 - asmedigitalcollection.asme.org
Geomembranes are essential impermeable materials commonly employed in the fields of
hydraulic engineering and geoenvironmental engineering. However, their long-term operation …