DrugCentral 2018: an update

O Ursu, J Holmes, CG Bologa, JJ Yang… - Nucleic acids …, 2019 - academic.oup.com
2018 release, we have continued to update, curate and add additional data types to the
DrugCentral … formulations, indications etc. were updated using manual and automated pipelines …

DrugCentral 2021 supports drug discovery and repositioning

S Avram, CG Bologa, J Holmes, G Bocci… - Nucleic acids …, 2021 - academic.oup.com
… Compared to the 2018 update, we note increases in the number of approved subtypes of
biologics, such as antibody-drug conjugates (60% increase), oligonucleotides (50% increase) …

DrugCentral: online drug compendium

O Ursu, J Holmes, J Knockel, CG Bologa… - Nucleic acids …, 2016 - academic.oup.com
… associated entities in DrugCentral are illustrated in Figure 1. DrugCentral is based on a …
and research codes that are continuously updated by automated monitoring of regulatory …

Exploring DrugCentral: from molecular structures to clinical effects

L Halip, S Avram, R Curpan, A Borota, A Bora… - Journal of Computer …, 2023 - Springer
… determined data from DrugCentral to support drug repurposing… and market accessibility,
DrugCentral provides valuable data … The latest update of DrugCentral introduced two age-based …

DrugCentral 2023 extends human clinical data and integrates veterinary drugs

S Avram, TB Wilson, R Curpan, L Halip… - Nucleic acids …, 2023 - academic.oup.com
… , DrugCentral has benefited from two major updates, in 2018 (2) … Thereby DrugCentral has
become an essential resource for … In the 2021 DrugCentral update, we separately calculated …

Assessing the public landscape of clinical-stage pharmaceuticals through freely available online databases

RH Griesenauer, C Schillebeeckx, MS Kinch - Drug discovery today, 2019 - Elsevier
… In 2018, Southan reviewed the largest chemical structure databases: PubChem, ChemSpider
and … Another unique feature of DrugCentral is an emphasis upon frequent updates by …

[HTML][HTML] Overview of the Knowledge Management Center for Illuminating the Druggable Genome

T Oprea, C Bologa, J Holmes, S Mathias… - Drug Discovery …, 2024 - Elsevier
… edition, DrugCentral has undergone two major updates, in 2018 10 and … Consequently,
DrugCentral has evolved into an … The current 2023 DrugCentral update delineates the additional …

DDInter: an online drug–drug interaction database towards improving clinical decision-making and patient safety

G Xiong, Z Yang, J Yi, N Wang, L Wang… - Nucleic acids …, 2022 - academic.oup.com
… The ATC code of each drug was extracted from DrugBank or DrugCentral, and the drugs …
to maintain and update the database. The data in DDInter will be updated every 6 months …

DrugComb update: a more comprehensive drug sensitivity data repository and analysis portal

S Zheng, J Aldahdooh, T Shadbahr… - Nucleic acids …, 2021 - academic.oup.com
… Here we report the major updates of DrugComb, a comprehensive data portal for the drug …
Furthermore, we have updated the network modelling of the drug combinations, such that the …

Therapeutic target database update 2018: enriched resource for facilitating bench-to-clinic research of targeted therapeutics

YH Li, CY Yu, XX Li, P Zhang, J Tang… - Nucleic acids …, 2018 - academic.oup.com
… an update of the Therapeutic target database (TTD) previously featured in NAR. This update
… This update makes TTD more useful for facilitating the patient focused research, discovery …