… ventilator method that uses an extended inspiratory time with an I:E ratio <1:1 (typically 2:1). …
2 levels or allowing a reduction in minute ventilation (V E ). On the other hand, some authors …

Sugars, primarily glucose and fructose, are the main energy source of cells. Because of their
hydrophilic nature, cells use a number of transporter proteins to introduce sugars through …

Sunitinib is an orally available small-molecule multikinase inhibitor. This agent potently
inhibits the vascular endothelial growth factor receptor, platelet-derived growth factor receptor, …

INTRODUCTION The emergence of three lethal coronaviruses in <20 years and the urgency
of the COVID-19 pandemic have prompted efforts to develop new therapeutic strategies, …

Background Few treatments with a distinct mechanism of action are available for patients with
platinum-refractory advanced or metastatic urothelial carcinoma. We assessed the efficacy …

… protein-2 in anti-IL-18-treated animals challenged with E. coli LPS, whereas IFN-γ and TNF
… -mediated tissue damage due to the reduction of either chemokines (E. coli LPS) or TNF (S. …

… e, IC 50 values calculated by nonlinear regression analysis. f, Cell-free luciferase … g, Cell-free
transcription and translation of luciferase mRNA in E. coli S30 lysates incubated with GST–…

The mycolic acid layer of the Mycobacterium tuberculosis cell wall is essential for viability
and virulence, and the enzymes responsible for its synthesis are targets for antimycobacterial …

Background Among patients hospitalized for community-acquired pneumonia (CAP), the
risk factors for short-term hospital readmission after discharge are unknown. Methods We …

Objective To assess the feasibility of a novel, partnered technology development process to
co-create mobile health applications (apps) addressing community health priorities, using …